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Overview of Acton lab projects and research questions
Overview of Acton lab projects and research questions 2016-2023 -
Multi-region TCR-seq data on ADAPTeR patient cohort
TCR-seq data for the manuscript 'Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma' -
Novel computational approaches to study CRC tumour microenvironment organoids...
Poster for the 2021 CRUK Cancer Evolution Symposium. Colorectal cancer (CRC) tumours present as a heterocellular setting where the colon epithelia harbouring oncogenic... -
Multi-region scRNA and scTCR data on ADAPTeR patient cohort
scRNA and scTCR data for the manuscript 'Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma'Samples: Tumour infiltrating lymphocyes taken from... -
Head and Neck Cancer Multivariate Blood Data
Data for the September 2021 submission to eLife. This is the source data for multivariate regression. Progression free survival outcome. Blood samples from 56 HNSCC patients... -
Exploring comorbidity prevalence in cancer
Comorbidities can have major implications for cancer care. They might impact the timing of cancer diagnosis, compromise optimal care, affect treatment outcomes and increase... -
Predicting One-Year Mortality in Older Cancer Patients: Performance of G8, SP...
The first aim was to compare, in a cohort study enrolling older adults (>65 years) with lung, gastrointestinal and prostate cancer, different easy measures of frailty... -
Corpora of patient information sheets and consent forms for UK cancer trials ...
Obtaining informed consent is an ethical imperative when conducting research involving human participants. However, participants’ actual level of understanding is often... -
Analysis of symptoms of rural workers exposed to pesticides
This cross-sectional study was conducted in southern Minas Gerais, in two counties: São Gonçalo do Sapucaí and Silvianópolis. Presented as objective to verify the important... -
How does the anti-tumor drug paclitaxel change the dynamics on breast cancer ...
Cells are complex systems where small fragments play an interdependent role. The functionality of these systems can be distinct at different length and timescales, depending on... -
AfterLife
Abstract: AfterLife (2003) is a heartfelt drama depicting the complex relationship between Kenny, an investigative journalist, and his sister Roberta, who has Down syndrome.... -
Data publication: The DRESDEN PLATFORM – A Research Hub for Ultra-high Dose R...
Source data, scripts and parts of figures to generate the figures in publication -
Exploring comorbidity prevalence in cancer
Comorbidities can have major implications for cancer care. They might impact the timing of cancer diagnosis, compromise optimal care, affect treatment outcomes and increase... -
Effect of capillary fluid flow on single cancer cell cycle dynamics, motility...
This dataset has no description
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FUCCItrack: an all-in-one software for single cell tracking and cell cycle an...
This dataset has no description
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FUCCItrack: an all-in-one software for single cell tracking and cell cycle an...
This dataset has no description
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IntOGen - Pipeline
Analyses somatic mutations in thousands of tumor genomes to identify cancer driver genes. Requirements: IntOGen depends on Python 3.4 or above and some python libraries. If you... -
OncodriveFML
Method to identify genomic regions, both coding and non-coding, bearing mutations with significant shift towards high functional impact across a cohort of tumos (FMbias), which... -
Raw data to support the manuscript with the following intended title: High-p...
Raw data of a set of experiments aimed to target cancer-associated PDGFR-β+ stromal fibroblasts. Generic methodologies used here are similar to those described in doi:... -
DCE-MRI (Dynamic Contrast Enhanced - Magnetic Resonance Imaging) prostate images
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of prostate cancer to facilitate its diagnosis. A 3mm slice fat-suppressed T2W fast spin-echo sequence (TR/TE/ETL:...