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RNA-seq of A.fumigatus strain Af293 with AfuTmV-2 mycovirus infected or Virus...
RNA-seq of A.fumigatus strain Af293. AfuTmV-2 mycovirus infected or virus free fungi were compared. Time point:just before the start of swelling (4 h after the start of... -
Aspergillus fumigatus Afs35
Aspergillus fumigatus is the pathogen which mainly causes the infectious disease, i.e. aspergillosis. A. fumigatus Afs35 is widely used as the laboratory strain, e.g. for... -
Transcription profiling by high throughput sequencing of the pathogenic fungu...
Aspergillus fumigatus Wild-type vs. mpkaA knockout (3 biological replicates each). Samples were sequenced using Illumina GAII (each sample one lane). -
Aspergillus fumigatus isolated from a plant bulb
Invasive fungal infections are increasingly endangered due to environmental disperse of antifungal resistance. In particular, azoles are widely used in agriculture as well,... -
Aspergillus fumigatus in Japan
The knowledge about genetic diversity of Aspergillus fumigatus strains from Japan remains limited. We sequenced A. fumigatus strains isolated from Japan and examined the genetic... -
Analysis of strains carrying cyp51A with N248K mutations using whole genome data
Among azole-susceptible clinical and environmental strains, some strains harbor N248K mutation in cyp51A gene. We investigated the cyp51A N248K strains phenotypically, analyzed... -
Copper homeostasis in Aspergillus fumigatus
The filamentous fungus Aspergillus fumigatus is the most important pathogenic fungus among Aspergillus species associated with aspergillosis. A. fumigatus is exposed to diverse... -
RNA sequencing of the treatment of Aspergillus fumigatus with the new antifun...
The mechanism of action of the new antifungal compound 089 was identified in Saccharomyces cerevisiae. The compound had antifungal effects also on pathogenic fungi. While on... -
Co-culture of Aspergillus nidulans and Aspergillus fumigatus
Fungal genomes contain genes for far more secondary metabolites (SMs) than have yet been identified in the laboratory. To explore silent SMs, co-culturing method has attracted... -
Drug resistance in Aspergillus fumigatus
Azole resistance of Aspergillus fumigatus is a global problem. This study explored genes contributing to azole tolerance in A. fumigatus by in vitro mutant selection with... -
Aspergillus fumigatus transcriptome analysis of the asexual developmental sta...
In order to gain insight into the role of AtfA transcription factor in conidia stress tolerance, we determined the expression profiles of the WT and atfA mutant at the... -
WGS of A. fumigatus collected from air sampling
Air sampling was carried out in 2018, and drug resistant A. fumigatus were sent for WGS. -
Aspergillus fumigatus WGS
We used next-generation sequencing (NGS) technology to identify mutations that arose during infection by A. fumigatus strains sequentially isolated from two patients: one with... -
Comparative transcriptomes between hyphae, conidial, and germinating conidia ...
We attempted to address the issue of dormancy mechanisms in Aspergillus conidia by performing a comparative transcriptome analysis within the genus. The transcriptome data were... -
RNA-seq of Aspergillus fumigatus IFM41362 vs IFM41362 mycovirus free strain
To characterize how A. fumigatus responded to AfuCV41362 infection, we performed RNA-seq analyses to compare gene expression between virus-infected and virus-free strains at two... -
Functional analysis of Aspergillus fumigatus AtrR transcription factor
Aspergillus AtrR-family proteins are identified as a transcription factor involved in azole resistance. The A. fumigatus AtrR regulates expression of cyp51A and cdr1B, encoding... -
Phenotype of azole-resistant Aspergillus fumigatus with a HapE mutation
We evaluated the resistance mechanism of azole-resistant Aspergillus fumigates with non-cyp51A mutations. As a result, the one splice site mutation was identified in the gene... -
Aspergillus fumigatus de novo genome assembly
Aspergillus fumigatus de novo genome assembly -
Small RNA sequencing of Aspergillus fumigatus
Aspergillus fumigatus is an important human pathogen and a leading fungal killer. This study aimed to determine the small RNA repertoire of A. fumigatus in conidia and mycelium... -
Genomic Surveillance of Aspergillus fumigatus Triazole Resistance in the Unit...
This study describes the genomic basis and mechanisms of triazole resistance in the United States