35 datasets found

Lipids form the major component of cell membranes, which separate the contents of the cell from the external environment. The oxidation of lipids within biological membranes is...

The presence of lung surfactant at the air-water interface of the lung is vital to prevent alveolar collapse. Exposure to environmental pollutants can cause the formation of...

Plastic bags are used as containers for storage of donated blood. These bags are often made of PVC plasticized with dialkylphthalates (e.g. DEHP), which migrates into the blood...

The yeast Candida glabrata is becoming an increasing cause of infections. We have developed RNA interference tools that allow us to study the virulence and resistance mechanisms...

We use chemistry to arrange unusual crystal structures that set up conflicting interactions between magnetic ions in the material. In these compounds i is not possible for a...

Cell membrane being the first line of defence of a complex cell, it forms an important scientific topic to study its encounter with various external entities. Nanoparticles are...

An increasing number of potential drug molecules are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant micelles is a...

Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of...

Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same...

Mineral aerosol in the atmosphere is a major part of the Earth’s aerosol budget. Organic films on these aerosols affect the aerosol’s ability to promote cloud formation and...

Cardiolipin (CL) is a structurally unique dimeric phospholipid localized in the inner mitochondrial membrane, which is known to provide essential structural and functional...

Surface-active molecules with water-loving and water-hating parts have been found to contribute substantially to the man-made urban aerosol load originating from cooking...

Amino acid based surfactants have been known for many years but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from...

Recently we have exploited non-equilibrium effects in the preparation of super-efficient polyelectrolyte/surfactant films at the air/water interface spread from the dissociation...

It is the aim of the proposal is to perform neutron reflectivity (NR) studies combined with contrast variation to determine the structure of phospholipid monolayers on a...

An number of potential drugs, including steroidal drugs are extremely water insoluble, limiting their commercialisation as medicines. Solubilisation of drug in surfactant...

Proteins are important in many applications ranging from the stabilisation of emulsions (oil-water interface) to foams (air-water interface). Understanding the relationship...

Tolaasin is a lipodepsipeptide (lipo = hydrophobic side chain, depsipeptide is an amino acid ring closed in a particular way) produced by strains of Pseudomonas tolaasii, and it...

This proposal is part of a broad programme of collaborative research between RAL / Oxford and Unilever, using predominantly scattering techniques to investigate the nature of...

Bilayer lipid membranes and their interactions with the integral or peripheral proteins serve as one of the key mechanism in various cellular functions like communication, cell...