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Adsorption of bioengineered antibodies at the oil/water interface
Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same... -
Neutron Reflection Studies on Adsorption of Myristoyl-L-Carnitine at the Air/...
The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to... -
Adsorption of Bispecific Monoclonal Antibodies with Extended Domains at the O...
Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same... -
Novel dual purpose antimicrobials and co-formulates to regenerate currently r...
The increased prevalence of antimicrobial resistant bacteria is the most significant challenge facing the human-health today in both developed and developing worlds. It's... -
Dynamic Adsorption of the Fusion Protein HSA-NEP at the Silica-Water Interface
HSA-NEP is a fusion protein with potential uses in treating Alzheimers disease. It consists of Neprilysin, a peptide degrading enzyme, linked to HSA, the most common protein in... -
Adsorption of Fab and Fc from monoclonal antibody at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how different globular proteins adsorb at the oil/water interface by neutron... -
Interactions between Designed Antimicrobial Lipopeptides and Inner Membrane L...
Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with... -
Neutron Reflection from a Biomineralisation Glycosaminoglycan on Calcite
Here we aim to structurally characterise the formation of adsorbed monolayers of heparin on calcite to address how these species influence biomineralisation and the inhibition... -
Adsorption of bioengineered antibodies at the oil/water interface
Following our previous study of adsorption of Fc, Fab and the constituent mAb COE-3, we continue to explore how two bioengineered mAbs adsorb at the oil/water interface by... -
Protein Adsorption at the PDMS Oil/Water Interface
Neutron reflection has been successfully used to measure the conformation of proteins adsorbed at the oil/water interface. However, in several such experiments, hexadecane has... -
Adsorption of Fab and Fc from monoclonal antibody at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how different globular proteins adsorb at the oil/water interface by neutron...