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Conformational analysis of subtilin / lipid II binary antibiotic/target membr...
Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the... -
Polarised neutron reflectometry measurements in magnetic antidots arrays.
This study aims to observe the magnetic properties of a family of arrays of permalloy antidots. Antidots are grown, by means of magnetron sputtering, on top of an anodised... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Effect of temperature on the structure of model wax films as studied by neutr...
Cuticular wax films protect plants by mediating water and nutrient transport from the environment. Surfactant is a key ingredient in agrisprays that can promote the uptake of... -
Polyoxometallate surfactant adsorption at solution surfaces
Polyoxometallates (POM) are well defined transition metal clusters with a range of interesting catalytic, magnetic and optical properties. To make efficient use of these... -
Surface structures of polycations in confined geometries
A second-generation surface force style apparatus has been developed to probe the inter-surface and near-surface structures under compressive forces. Systems of current academic... -
Reflectometry studies of the mechanism of formation of mesoporous silicate fi...
Surfactant-silica self-assembly processes have been extensively studied since the discovery of M41S mesoporous materials in 1992. Mesoporous silicate films can be grown from... -
The hydrophobic interaction A peptides and a lipid monolayer at the o...
This proposal relates to the study on the fundamental level, the hydrophobic interaction A peptides and a lipid monolayer at the oil-water interface. NR will be used to... -
Modelling of surfactant phase behaviour versus concentration below ambient te...
We wish to understand how the concentration of surfactant mixtures in solution affects adsorption at lower temperatures; in particular, we wish to see how the composition of the... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
Electric field induced swelling/collapse of strong polyelectrolyte brushes
Electric field induced changes in the swelling of a strong polyelectrolyte brush will be investigated using neutron reflectivity. A poly(styrene sulphonate), PSS, brush will be... -
Investigation of the interactions of perfluoroalkyl substances with model wor...
Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable... -
Antimicrobial Mechanisms of Model Biocides via Their Interaction with Lipopol...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Neutron Reflectometry of Tethered Microphase Separated Block Copolymers
Neutron reflectometry will be used to probe the scattering length density profile in tethered films of block copolymers grafted onto silicon substrates. The tethered... -
Structure of Confined Salivary Films
Lubrication by saliva is a key factor in oral health and food consumption. It is know that salivary lubrication is mediated by the thin proteinaceous film i.e., the pellicle,... -
Membrane Composition-Dependent Interaction between Beta-Arrestins and Lipid M...
Beta-arrestins are proteins that regulate GPCR signaling, e.g. by recruiting endocytic components to remove the receptor from the plasma membrane. Our fluorescence microscopy... -
Neutron reflection study of effects of non-ionic alkyl ethoxylates on model w...
We propose to use NR to study the structural features of the model wheat wax films formulated from the known main components of long chain primary alcohols and an ester. By... -
Effect of Aging Temperature on Inorganic Films Templated by Polymer-Surfactan...
Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the... -
Non-local electrodynamics effect in an ¿extreme¿ low-k superconductor
We intend to perform accurate measurements of the magnetic field profile in the Meissner state of an ¿extreme¿ low-k superconductor (In, k = 0.06, k is the Ginzburg-Landau... -
Quantifying the Asymmetry in Cell Membrane Mimetic Supported Lipid Bilayers.
Cell membranes are characterised by complex lipid composition and asymmetric distribution of lipids (lipids facing the outside of the cell are different from the lipids that are...
