-
New Approaches to Producing Floating Supported Bilayers
The complex sample environment needed for floating supported bilayers has often led to a need to constantly redevelop the system to improve reproducibility. Here we plan to... -
DINS study of the isotopomers of water
This dataset has no description
-
Direct Observation of Gram Negative Bacterial Membrane Disruption by Supramol...
Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the... -
Can surfactants be pushed out of polymer layers by applying compression?
For many applications such as paints, foods and drug formulations, aggregation of colloidal particles is prevented by combining polymer and surfactant adsorption. Key to this... -
Antibiotic paths through the bacterial outer membrane: The strange case of va...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Study of protein adsorption tuned via multivalent ions and the influence of s...
Protein adsorption at solid-liquid interfaces plays a key role in biomedical technologies such as biosensors or biomaterials for medical implants. Despite considerable progress... -
Novel block bottlebrush polyelectrolytes: The effect of cationic block charge...
In this work we will study a novel block copolymers consisting of a linear cationic block and uncharged bottle-brush block having 45 units long poly(ethylene oxide) side chains.... -
Elucidating the Membrane Interaction Mechanism of Chloride Intracellular Chan...
Chloride Intracellular Channels (CLICs) are a family of 6 proteins that have in common a C-terminal CLIC module and chloride-selective ion channel activity. CLIC1 is a 241... -
Interaction of lamellar and non-lamellar lipid mesophases with inorganic nano...
The behavior of inorganic nanoparticles (NPs) with biological interfaces is a key research topic, to boost Nanomedicine development. In this respect, 2D lipid assemblies are... -
Frustrated Lewis pairs: encounter complexes in an ionic liquid
Frustrated Lewis Pairs (FLPs) are combinations of bulky Lewis acids and bases, which cannot form acid-base complexes due to steric hindrance. They are capable of metal-free H2... -
Solvent-solute interations in PET recycling systems
Glycolysis of polyethylterephthalate (PET) catalysed by ionic liquid solvents could offer a metal-free low cost approach to chemical recycling of waste PET. This work will... -
The Orientation and Conformation of an Enantiomeric Pair of 310 Helical Pepti...
We wish to investigate the interactions between peptide mimics of peptaibols, a highly active class of natural antimicrobial peptide, and membranes. In particular we are... -
Spontaneously Segregated Polymer Brush Structure
This study intends to elucidate how molecular hairy or brush-like structures form on different flat surfaces. When molecule chains form a densely packed assembly on a surface... -
WATER DYNAMICS IN FERROFLUIDS
Magnetic fluids are used in conjunction with applied magnetic fields in several medical applications including drug and gene delivery, imaging and hyperthermia cancer therapy.... -
Novel Alginate Adsorption onto High Surface Energy Crystal Faces of Calcite
In this novel proposal we will investigate adsorption onto the non-equilibrium face of calcite the first time this has been attempted. This will compliment and extend our... -
Assessing the interactions of cyclic peptide-polymer conjugates with a lipid ...
Cyclic peptide-polymer nanotubes can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. As such, understanding how... -
Neutron diffraction for non-destructive evaluation of composition and microst...
Recent analytical research on ancient metal objects recovered in Mongolia revealed that the early bronze and iron-making technologies can be clearly differentiated from those... -
Structure and solvation of LiNTf2/1,2,3-trimethoxypropane - a new bio-derived...
This work will study the structure a new lithium-based electrolyte produced using 1,2,3-trimethoxypropane, a bioderived low-toxicity green solvent, as a first stage towards the... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
A biophysical approach of studying the molecular interactions of a novel anti...
Gram negative (-ve) bacteria possess numerous defenses against antibiotics, not the least of them being the intrinsic permeability barrier afforded by their outer membrane (OM)...
