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Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS... -
Competition at the nanoparticle surface: one polymer, two surfactants, many p...
Polymers and surfactants are key components in detergency. Understanding their interactions is essential to formulate smartly. Detergent formulations usually contain a mixture... -
Self-assembly of GFP-HMPA protein polymer conjugates: Effect of polymer hydro...
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation... -
Molecular Collapse and Conformation of Low Molecular Mass Polyacrylic Acid an...
There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at... -
Polymer displacement by surfactant at colloidal interface
The interactions of neutral polymers with surfactants have a key role in detergency and are systems of current academic and commercial interest. Here, we propose to study the... -
Structure determination of solution aggregation of single alkyl chain PC surf...
We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of... -
Characterisation of novel, sequence specific protein/protein and protein/DNA ...
Gene (nucleic acid) delivery to the cytosol or nucleus of a cell is, without the aid of a suitable delivery system, an inefficient process. Here the interaction of a defined... -
Aggregation behaviour in solution of cationic conjugated polymers and oligomers
In the proposed experiments we extend previous work on characterization of aggregates formed by cationic conjugated polymers and oligomers in water. Particular emphasis will be... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic... -
Emusifier distribution in concentrated dispersions
Emusifier distribution in concentrated dispersions -
Mixed surfactants for positive synergism in dense CO2
This proposal aims to explore a cheaper and more environmental-benign surfactant system for yielding efficient water/CO2 microemulsions. The new surfactants permit high... -
Ligand conformation at semiconductor nanoparticle surfaces for high-efficienc...
The efficiency of silicon solar cells is limited to 29%. One possible way of breaking this limit uses a process called singlet fission, converting a high energy photon into two... -
Structure of Cellulose Nanofibril Gels with Different Surfactants
This proposal is part of a project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils and small amounts of additives, such...
