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Examination of the Membrane Structure of Live Bacteria using Neutron Reflecto...
We propose to investigate in-vivo cell membrane structure of gram-positive (B. subtilis) and gram-negative (S. oneidensis) bacteria adhered to a silicon oxide surface using... -
Adsorption and activity of Thermomyces lanuginosus Lipase (TLL) at the oilwat...
The purpose with the proposed project is to provide a better understanding of structural changes in interfacial lipid layers due action of lipolytic enzymes. In this study we... -
Probing the interactions of chitosan with lipid bilayers to elucidate its ant...
Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and... -
Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
The structure and orientation of the Bam complex in the Gram-negative outer m...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterialsurvival, from providing basic physiological functions, to aiding virulence and... -
Assembling Biomimetic layers on monolayers of Gold Nanoparticles
Gold provides a high quality surface on which to arrange biomolecules such as proteins since we can use cysteine amino acids to deliver gold thiol chemical bonds which can... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Investigating the Surface Structure of Ionic Liquid Mixtures using Neutron Re...
The structure of ionic liquid (IL)-gas interfaces is currently a hot topic in the field and understanding of the surface structure of pure ILs is improving. However, very little... -
Copy of: ATmospheric Oxidation of MIxed films studied by Neutron Reflectometr...
Quantifying amount, composition and fate of surface-active organic aerosols originating from cooking processes is a key atmospheric research activity. Our project aims to... -
Study of the multi-gap phenomena in SrTiO$_3$
We intend to perform the magnetic field penetration depth \lambda measurements on theoxygen reduced and Nb-doped SrTiO_3 -- the first oxide superconductors where two-gap... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Effects of confinement on polymeric surfactants
Polymeric stabilisers are often used in the preparation of emulsions and dispersions of particles. The purpose of this additive is to help keep the mixture stable so that it can... -
Adsorbtion from nematic mixtures
The aim is to measure the preferential adsorption of one component in a nematic mixture. The base is 4-pentyl 4¿- cyanobiphenyl (5CB) and it is doped with 4-pentyl 4¿-... -
Study of the interfacial self-assembly of peptide/polymer membranes by neutro...
The interfacial self-assembly between large (polymer) and small (peptide) molecules of opposite charge results in the formation of highly organized membranes. Furhter... -
Outer membrane mimics using novel thiol-PC
We have recently shown that dense monolayers of PC can be assembled on gold surfaces using a new omega thiol PC from Avanti. This has two advantages over our previous methods.... -
The effect of dendrimer surface functionalization on the interaction with mod...
Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across... -
Effect of membrane fluidity for novel dendrimer drug interaction and uptake m...
Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel... -
Investigating the structure of the pulmonary lung surfactant at the air-water...
The lung surfactant is a film coating the alveolus of the lung. We want to characterize the structure of this film at the air-water interface at a molecular level. This will... -
Adsorption of cationic surfactants to Al2O3
A recent experiment has provided clear evidence for a large maximum in the adsorption just below the critical micelle concentration of the surfactant hexadecyl trimethyl... -
Surfactant adsorption onto model surfaces
In the context of home and personal care products, studying surfactant and mixed surfactant adsorption ion model solid surfaces, which mimic real surfaces such as fabrics, hair...