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RNA-seq analysis of doxycycline-regulated gene expression in Aspergillus fumi...
To determine the genes responsive to FfmA in A. fumigatus, a doxycycline-repressible (dox off) gene fusion to the ffmA coding sequence was constructed. This strain was... -
Whole Genome Association Study for Itraconazole Sensitivity in Aspergillus fu...
Our goal in this study is looking for the genes that contribute to itraconazole sensitivity in Aspergillus fumigatus. -
Fludioxonil-induced differential gene expression in Aspergillus fumigatus and...
The antifungal compound fludioxonil targets the fungal specific group III hybrid histidin kinaseTcsC of A. fumigatus, which in turn activate the High Osmolarity Glycerol (HOG)... -
Analysis of strains carrying cyp51A with N248K mutations using whole genome data
Among azole-susceptible clinical and environmental strains, some strains harbor N248K mutation in cyp51A gene. We investigated the cyp51A N248K strains phenotypically, analyzed... -
Quantification of Bir1-dependent differential gene expression in swollen Aspe...
This study aimed to understand the differences in gene expression when comparing Aspergillus fumigatus swollen conidia that overexpress an artifical Bir1 construct (strain... -
Aspergillus fumigatus A1163 Raw sequence reads
mRNA profiles of Aspergillus fumigatus A1160 wild type (WT) and sas3 KO mutant -
Environmental Aspergillus fumigatus isolates from the east and west coasts of...
We sampled 52 sites on the east and west coasts of the U.S. for A. fumigatus. We sequenced 135 isolates and compared them with other publicly available U.S. and worldwide isolates. -
Gene expression changes in the absence of the carbon catabolite repressor, CreA.
This experiment was designed to test the change in gene expression in the absence of the transcription factor, CreA. Two media conditions were tested to determine the role of... -
Whole genome sequencing of clinical Aspergillus fumigatus isolates from the U...
Whole genome sequencing was performed on 26 clinical isolates of A. fumigatus originally isolated from patients in the United States, to identify genetic determinants of... -
Aspergillus fumigatus CEA10 Transcriptome or Gene expression
To further define hypoxia response and confirm SrbA regulation of genes with associated SrbA DNA binding events in their promoter regions, RNA-seq analysis of the transcriptome... -
Differentially expressed genes in an Aspergillus fumigatus mitochondrial fiss...
Analysis of differentially expressed genes in an Aspergillus fumigatus mitochondrial fission/fusion mutant (delta-dnm1 mgm1-tetOn) relative to wild... -
Copper homeostasis in Aspergillus fumigatus
The filamentous fungus Aspergillus fumigatus is the most important pathogenic fungus among Aspergillus species associated with aspergillosis. A. fumigatus is exposed to diverse... -
Aspergillus fumigatus meiosis study
Genome assemblies of two parental strains of Aspergillus fumigatus and sequence data of 195 offspring -
Genome-wide transcriptional changes under oxidative stress in iron-starved As...
Aspergillus fumigatus has to cope with a combination of several stress types in the human body, and the interplay between the different stress responses can significantly... -
Multiazole resistance in clinical and environmental fungal isolates
Whole genome sequencing of SYBARIS Aspergillus spp. known to be multi-drug resistant and difficult to treat. Aim of this eaperiment is to investigate the genetic basis of... -
Aspergillus fumigatus Transcriptome analysis in response to calcium exposure
Aspergillus fumigatus Transcriptome analysis in response to calcium exposure -
Characterization of regulators of G protein signaling, rgsD and rax1 of Asper...
RgsD functioned in asexual development and melanin synthesis. Rax1 involved in the protection against oxidative stresses. Overall design: Examination the transcriptomes of the... -
Aspergillus fumigatus transcriptome sequencig: protein phosphatase PpzA is in...
Iron restriction imposed by mammalian hosts during an infection is a common mechanism of defense to reduce or avoid the pathogen infection. Iron is essential for organism... -
Dual-RNA sequencing of dendritic cells challenged with Aspergillus fumigatus
Dendritic cells and A. fumigatus were co-cultured with two different MOIs (1 or 0,5) for 2, 4 or 6 hours. Single-cultures of dendritic cells and A. fumigatus serve as controls.... -
RNA sequencing of the treatment of Aspergillus fumigatus with the new antifun...
The mechanism of action of the new antifungal compound 089 was identified in Saccharomyces cerevisiae. The compound had antifungal effects also on pathogenic fungi. While on...