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Oxidation of thin film at the air-water interface of cloud droplets using REA...
The Earth's climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important effects. Common... -
Effect of squalene on membrane structure and Amphotericin B resistance in Can...
The yeast Candida glabrata is becoming an increasing cause of infections. We have developed RNA interference tools that allow us to study the virulence and resistance mechanisms... -
Study of the interfacial self-assembly of peptide/polymer membranes by neutro...
The interfacial self-assembly between large (polymer) and small (peptide) molecules of opposite charge results in the formation of highly organized membranes. Furhter... -
Structural insight into the mechanistic process of permeabilization into mode...
The aim of this study is to try to understand how antimicrobial peptides bind to model lipid monolayers mimicking different cell membrane types. Following our previous work,... -
Interfacial Adsorption of Soluble Amino-Acid Based Surfactants in Mixtures wi...
Amino acid based surfactants have been known for many years, but so far few detailed studies have been carried out on their properties. We are using amino acids extracted from... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Proof of principle: Can ecotoxological partition constants for persistant org...
A proof-of-principle experiment to use the convenient scattering length of perfluorinated alkyl surfactants to measure partitioning to lipids at the air-water interface,... -
Water adsorption isotherms for Nafion
Electroceuticals is the attempt to speak the electrical language of the nerves to achieve higher treatment effect. Thus, the search is on to develop devices to enhance... -
Structure and conformation of thermo-responsive nanogels at air/water interfa...
Soft polymeric nanoparticles possess many interesting properties. Those based on N-isopropylacrylamide are surface active and respond to changes in temperature. This give rise... -
Copy of: ATmospheric Oxidation of MIxed films studied by Neutron Reflectometr...
Quantifying amount, composition and fate of surface-active organic aerosols originating from cooking processes is a key atmospheric research activity. Our project aims to... -
Joint Diamond/ISIS proposal 22078
The basis of a biological cell membrane is a lipid bilayer containing functional proteins. Its purpose is to form a selective barrier that separates the aqueous fluids inside... -
Characterisation of newly ordered sapphire blocks
This dataset has no description
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The Effect of the Head Group on Multilayering of Alkanoic Alkyl Ester Sulphon...
We have shown that under certain conditions multilayer adsorption of surfactants occurs at the air-water interface. in which case the system becomes a powerful wetting agent (it... -
Structure of antibiotic mixtures in lung surfactant membrane models at the ai...
Clarithromycin and Levofloxacin are essential antibiotics used to treat bacterial infections such as tuberculosis and pneumonia. Lung surfactants may be used as drug carrier of... -
Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
Impact of Stereochemistry and Diamine Structure on Absorption of Constructed ...
Chiral gemini surfactants containing stereogenic centers and two amphiphilic moieties, not only maintain the chiral properties, but also exhibit stronger aggregation properties,... -
Binding studies of Quantum Dots and Pore-Forming Proteins on multi-component ...
Cell membrane being the first line of defence of a complex cell, it forms an important scientific topic to study its encounter with various external entities. Nanoparticles are... -
Mixed H/F-Carbon surfactant monolayers for fire-fighting applications
The aim is to use Neutron Reflectivity (NR) to gain essential information on the adsorption properties of fluorocarbon/ hydrocarbon mixtures in commercial fire-fighting foam... -
Oxidation of thin film at the air-water interface of cloud droplets using REA...
The Earth's climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important effects. Common... -
Interplay of apoptosis regulating Bcl-2 proteins at mitochondrial membranes u...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). This pathway is a major regulator in cell...
