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New Approaches to Producing Floating Supported Bilayers
The complex sample environment needed for floating supported bilayers has often led to a need to constantly redevelop the system to improve reproducibility. Here we plan to... -
Antibiotic paths through the bacterial outer membrane: The strange case of va...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Novel block bottlebrush polyelectrolytes: The effect of cationic block charge...
In this work we will study a novel block copolymers consisting of a linear cationic block and uncharged bottle-brush block having 45 units long poly(ethylene oxide) side chains.... -
Study of Deep Eutectic Solvents dilutions: nanometer size domains and molecul...
Carbon materials with nanopore structures are of great importance for development of energy storage and gas adsorption devices. The critical parameter is pore size and it is... -
Interaction of lamellar and non-lamellar lipid mesophases with inorganic nano...
The behavior of inorganic nanoparticles (NPs) with biological interfaces is a key research topic, to boost Nanomedicine development. In this respect, 2D lipid assemblies are... -
Frustrated Lewis pairs: encounter complexes in an ionic liquid
Frustrated Lewis Pairs (FLPs) are combinations of bulky Lewis acids and bases, which cannot form acid-base complexes due to steric hindrance. They are capable of metal-free H2... -
Understanding Melt Phase Aggregation in Semicrystalline Polymer Blends
We have recently prepared and studied the surface properties of some well-defined multi-end functional polyethylenes. Whilst most of our surface studies indicate that these... -
Solvent-solute interations in PET recycling systems
Glycolysis of polyethylterephthalate (PET) catalysed by ionic liquid solvents could offer a metal-free low cost approach to chemical recycling of waste PET. This work will... -
The origin of the dissolution of cellulose in NaOH/urea aqueous solution at -...
Cellulose is produced over tens of billions of tons every year in the world. It is the one of the most abundant natural polymer resources. Compared with petroleum-based... -
Structure and solvation of LiNTf2/1,2,3-trimethoxypropane - a new bio-derived...
This work will study the structure a new lithium-based electrolyte produced using 1,2,3-trimethoxypropane, a bioderived low-toxicity green solvent, as a first stage towards the... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
A biophysical approach of studying the molecular interactions of a novel anti...
Gram negative (-ve) bacteria possess numerous defenses against antibiotics, not the least of them being the intrinsic permeability barrier afforded by their outer membrane (OM)... -
Solvation structure of sodium ions and hexa-fluorophosphate ions in organic c...
Here we propose to study the local structure of sodium in standard organic carbonate electrolytes for sodium ion batteries. Three different electrolytes are chosen to study; a... -
Impact of Elasticity on Surface Wetting
We have recently characterised a surface wetting transition for a low molecular weight oligomer in a high molecular weight rubbery polymer. Although weak surface segregation of... -
Composition depth profiling of novel spray-coated plastic solar cell materials
We propose to study a range of new lower energy gap organic photovoltaic (OPV) materials deposited by spray coating using neutron reflectivity. The new materials to be studied... -
Exploring the interactions between vesicles/viruses and supported lipid bilay...
Many biological processes occur at the interface of cells, at the so called cell membrane, such as internalization of biological nanoparticles, including virions, exosomes and... -
Effect of membrane fluidity for novel dendrimer drug interaction and uptake m...
Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel... -
Structure of Li4.4In0.4Sn0.6S4
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The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
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The Effect of Core Oligosaccharide Size on the Binding of Antimicrobial Prote...
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