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Neutron Reflectivity study of lipopolysaccharide complexes with lateral domai...
We propose to investigate the role of lateral phase separation on LPS insertion into model membranes and the effects of target membrane structure and composition. A comparison... -
Antimicrobial Peptide Binding & Rearrangement in Model Membranes ¿ Building a...
Antimicrobial peptides (AMPs) are attractive drug candidates because of their selectivity and speed of action against bacteria. We have developed a novel approach to delivering... -
Adsorption of concentrated Aerosol-OT to Sapphire ¿ the effect of divalent sa...
AOT is also known to be very sensitive to the concentration and nature of counter-ions. When adding a sufficient amount of divalent salt to an AOT solution, a very strong Bragg... -
Studying the helimagnetic order and precursor phenomena in MnSi under pressure
The archetype chiral system MnSi belongs to the family of non-centrosymmetric cubic helimagnets where a helimagnetic ordering exists below the critical temperature of 29 K. This... -
Interaction of thermo-responsive deutrated nanogels with lipid monolayer at t...
Drug delivery through skin is an important delivery route. However, the outermost layer of the skin provides a formidable barrier to dermal absorption and penetration for... -
Effect of alkyl chain length on the adsorption of n-alkyl phosphocholine surf...
This proposal relates to the study of adsorption of n-dodecyl phosphocholine (C12PC) at the oil-water interface. The thickness of the adsorbed monolayers measured for dC12hPC... -
Interactions of modified clupeines with Gram-negative model bilayers
Clupeine is isolated from herring and is an example of a protamine, which are cationic antimicrobial peptides occurring in the sperm cells of some fish. Protamines are active... -
Incorporation of PAN-pyrene swollen micelles in crosslinked polyelectrolyte f...
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the micelles... -
Neutron Reflectivity Study of Antimicrobial Peptides Interacting with Lipopol...
The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by... -
Understanding the Affect of Lipid Tail Saturation on Anaesthetic Interaction ...
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Interfacial adsorption of monoclonal antibody and antigen binding
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Model biomembrane dendrimer interactions
The objective of the present study is to investigate the interaction between PAMAM dendrimers and solid supported model biomembranes of high fluidity. These membranes consist of... -
Structural modelling of meibomian lipid films
Meibomian lipids spread on the surface of tears to enable formation of a stable film. Our data show that meibum forms duplex films that have physical properties not emulated by... -
The Structure of Ca- and Yb-ammonia Solutions: Polarons, Bipolarons and Elect...
In this experiment we propose to perform diffraction on isotopically substituted samples of Ca/Yb:ND/H3 and Ca/Yb:15ND3 at two concentrations (8 and 2 MPM) using the new NIMROD... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
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Iron Oxide Nanoparticle Interactions with Lipid Bilayers in a Magnetic Field
Iron oxide nanoparticles are one of the first nanomaterials to be approved for use in the body. However, research into particle binding and incorporation to, as well as... -
An investigation on the adsorption of reverse pluronic and additives on metal...
PPO-PEO-PPO copolymer-based lubricant with extreme pressure or friction modifier additives has been introduced as boundary lubricant in metal forming. The Pluronic reverse... -
Adsorption of benzotriazole onto copper/copper oxide surface from non-aqueous...
Benzotriazole (BTAH) has been known to be a very effective corrosion inhibitor for copper and its alloys. Adsorption of BTAH from oil is a relatively less researched area... -
Surface activity of biosurfactant (sophorolipid) / surfactant mixtures
Understanding the fundamental aspects of the surface adsorption and self-assembly of biosurfactant and biosurfactant / conventional surfactant mixtures is a major challenge for... -
Conformation of lipid, DSPC and cholesterol mixture
In this proposal we intend to investigate the intermolecular interactions in a mixed phospholipid/cholesterol monolayer at the oil-water interface using neutron reflectometry....
