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Part B: Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic l...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Surface composition in the physical developer process for latent fingerprint ...
Physical developer (PD) is a latent fingerprint development technique that is highly effective on paper and related surfaces, notably banknotes. The process exploits a redox... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Using the nano discs approach at surfaces to determine the relation between s...
Membrane bound proteins continue to be to date the most elusive molecules in nature, since they are only functional in the lipid bilayer. We have developed a method to study... -
Assembling floating, very sparsely tethered, protein-lipid bilayers.
We have recently used Polref in to measure the assembly of tethered floating lipid bilayers. These are useful models of biological membranes in which a phospholipid bilayer is... -
SXD investigation of post pressurised Cs2CuCl4
Cs2CuCl4 has been extensively studied using neutron scattering, and has revealed a quantum spin liquid phase below 2.8 K with antiferromagnetic interactions, and long range... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their... -
Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. We very recently oxidised... -
Interplay of apoptosis regulating Bcl-2 proteins with mitochondrial membranes...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Speciation and complex-ion formation in protic ionic liquids
The aim of this proposed study is to explore protic ionic liquids formed from by combining bis{(trifluoromethyl)sulfonyl}imidic acid (H[NTf2]) with imidazole and pyridine at... -
Electrostatic Interactions between Floating Bilayers and Thiol Coated Interfa...
Bilayers which float below a self-assembled monolayer (SAM) coated solid support represent one of the most advanced membrane mimetics. Recently (RB 1720155) we assessed the... -
Neutron reflectivity studies on bulk heterojunction (BHJ) thin films
Polymer solar cells (PSCs) open up new perspectives in the solar cell market. The morphology of the active layer of PSCs plays a crucial role on the corresponding devices... -
Examination of Free Floating Models of the Gram-Negative Bacterial Outer Memb...
This dataset has no description
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A new approach to monitoring copper corrosion using polarised neutron reflection
The aim of this experiment is to test a new approach to monitoring the corrosion of copper using polarised neutron reflection to simultaneously measure two contrasts with time.... -
Membrane-stacking Properties of Mutant Myelin Proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Structural Observation of the Self-Assembly Kinetics of Cyclic Peptide Nanotubes
Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the... -
The interaction of C6Hx (x = 6, 8, 10, 12) with Raney Ni
Fuels such as diesel contains different kinds of aromatic and poly aromatic compounds, which on their combustion emits environmental pollutants such as SOx, NOx, COx, and... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
This dataset has no description
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Non-lamellar lipid-based liquid crystalline structures at interfaces - effect...
To understand better the properties of non-lamellar liquid crystalline nanoparticles, LCNP, as delivery vehicles or surface modifying systems, it is crucial to understand how...
