-
Effect of Phosphatidylserine lipids on Tissue Factor structure and function i...
Tissue Factor (TF) is the membrane protein responsible for the initiation of the blood coagulation process [1]. In case of a vessel injury, the TF is exposed to the blood stream... -
Helimagnetic correlations in FeCl3
The recent discovery of skyrmions and skyrmion lattices in materials with no inversion symmetry and their corresponding potential applications of Skyrmions in magnetic... -
Biological membrane mimics made of deuterated lipids extracted from E. coli
Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular... -
Surfactant Adsorption in Multi Metal Deposition Fingerprint Enhancement
Multi metal deposition (MMD) is a new latent fingerprint enhancement technique that is extremely effective on plastics, including drug wraps and explosives wrapping; it is also... -
Seizing Membrane Proteins - Cytochrome P450 Reductase in Nanodiscs
This proposal seeks to shed light on the functional and structural characteristics of a specific membrane protein - cytochrome P450 reductase (abb. POR) - part of the cytochrome... -
Membrane reconstitution of human dihydroorotate dehydrogenase using lipid-det...
Human dihydroorotate dehydrogenase (DHODH) is an integral membrane protein found in mitochondria involved in the biosynthesis of pyrimidines. DHODH oxidizes dihydroorotate with... -
Part B: Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic l...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
Surface composition in the physical developer process for latent fingerprint ...
Physical developer (PD) is a latent fingerprint development technique that is highly effective on paper and related surfaces, notably banknotes. The process exploits a redox... -
Antibiotic binding to a bacterial outer membrane model containing oriented pr...
The Outer Membranes (OM) is a feature of many pathogenic bacteria. It is important as a barrier to antibiotics & the site of human-bacteria interaction. However bacteria are... -
Using the nano discs approach at surfaces to determine the relation between s...
Membrane bound proteins continue to be to date the most elusive molecules in nature, since they are only functional in the lipid bilayer. We have developed a method to study... -
Assembling floating, very sparsely tethered, protein-lipid bilayers.
We have recently used Polref in to measure the assembly of tethered floating lipid bilayers. These are useful models of biological membranes in which a phospholipid bilayer is... -
A total scattering study of the concentration and temperature dependence of s...
Lithium-ion batteries (LIBs) are ubiquitous in our portable electronics, however they are ill suited for applications where cost or sustainability are of paramount importance,... -
Compression-induced martensitic transformations in Ni2MnGa ferromagnetic shap...
The Heusler alloys based on Ni2MnGa are considered as promising new multifunctional material showing magnetic shape memory effect related to the giant magnetic field induced... -
Tuneable Adsorption of Soft Colloids on Model Biomembrane
Understanding how nanoparticles interact with lipid bilayers will potentially have high impact on the development of new drug delivery systems, and on the investigation of their... -
Oxidation of gram-negative cell-wall proxy with OH radicals - kinetics and me...
Hydroxyl radicals may be used as disinfection agent in the advanced oxidation processes or tertiary treatment of waste and occasionally drinking water. We very recently oxidised... -
Interplay of apoptosis regulating Bcl-2 proteins with mitochondrial membranes...
Mitochondria are not only the powerhouse of the cell, but are also involved in cellular suicide via apoptosis (programmed cell death). The mitochondrial apoptotic pathway is a... -
Speciation and complex-ion formation in protic ionic liquids
The aim of this proposed study is to explore protic ionic liquids formed from by combining bis{(trifluoromethyl)sulfonyl}imidic acid (H[NTf2]) with imidazole and pyridine at... -
Electrostatic Interactions between Floating Bilayers and Thiol Coated Interfa...
Bilayers which float below a self-assembled monolayer (SAM) coated solid support represent one of the most advanced membrane mimetics. Recently (RB 1720155) we assessed the... -
Lipid bilayers suspended beneath the air/water interface for neutron reflecti...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,...
