-
Adsorption of modified PEI / SDS mixtures at the solid-solution interface
Polymer-surfactant mixtures are extensively used in a wide range of domestic, industrial and technological applications. This proposal is part of a collaboration between Oxford... -
Charged nanogels interactions with model lipid membranes
In recent years nanogels show great potential as drug delivery systems. Especially dermal drug administration which is non-invasive, helps to avoid the first-pass effect with... -
Neutron reflectivity study of phase separation in polymer-drug thin films
Nearly 40% of new chemical entries are poorly water-soluble. Drug encapsulation into water-soluble polymers is an active research area owing to the ability of improving drug... -
Scaling Model for the adsorption of macromolecules at the oil-water interface
The aim of this proposal is the application of the scaling model for the adsorption of proteins at the oil-water interface. The adsorbed amount for a series of oils as a... -
Interfacial adsorption of single alkyl chain PC surfactants (CnPmC)
We propose to investigate the interfacial adsorption of a series of water-soluble single chain PC surfactants using neutron reflection, focusing on assessing the effects of... -
Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Neutron Reflection at the Mica Water Interface
Mica is an exceptionally important mineral in surface science, which until now has been inaccessible by neutron reflection. Here we propose a novel attachment method unlocking... -
How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Inter...
In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on... -
A study of hole injection efficiency for a model conjugated bilayer system
Polymer-based electronics have attracted huge interest due to their wide applicability to light emitting diodes, field effect transistors and photovoltaics. The aim of our... -
Interactions between a polymer brush grown from a macro-initiator-modified sa...
We propose to make neutron reflectivity measurements of the weak polyelectrolyte, poly(dimethy amino ethyl methacrylate), grown from two different surface densities of initiator... -
Spray-coating plastic solar cells: New materials & innovative processes for O...
We propose to study a range of new selenium containing lower energy gap organic photovoltaic materials deposited by spray coating using neutron reflectivity. The new materials... -
Neutron reflection from 3He layer adsorbed on liquid 4He surface
More than four decades ago A. F. Andreev predicted theoretically the existence of quantum states of 3He atoms on free surface of liquid 4He . In other words, at low... -
Membrane-stacking Properties of Mutant Myelin Proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Interaction of the nucleic acid, DNA, with a model biomembranes of varying ri...
In this experiment we aim to investigate, using neutron reflectometry in combination with contrast variation, the intermolecular interaction between the nucleic acid, calf... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
Does Sulphate radical anion oxidse cloud organic matter in the atmosphere?
Projected climate change is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and reflectivity, important climatic effects.... -
Temperature Dependence of the Oxidation of Monolayers Under Atmospheric Condi...
The Earth¿s climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects cloud droplet size and optical properties, important climatic... -
Neutron reflectometry study of liquid helium surface
In our recent experiment RB1120146 we have obtained new exciting results on neutron scattering on liquid He surface. At 1.5 and 2.3K there was no difference in reflectivity...
