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Investigating the effect of nanoparticles on PBI self assembly
The generation of hydrogen from water using light could be a method of providing a clean fuel, which is clearly important for our growing energy needs. We are using perylene... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
The structure of the Bam complex, the Gram-negative outer membrane protein fo...
The proteins of the outer membrane of Gram-negative bacteria are critical for bacterial survival, from providing basic physiological functions, to impairing virulence and... -
SANS studies of the micellar structure of C12-L-Carnitine and C14-L-Carnitine...
Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use... -
Mechanisms of shear stability in emulsions
High internal phase water-in-oil emulsions can be efficiently stabilised by polymer amphiphiles for a static emulsion, and also show high shear stabillity even at elevated... -
Molecular Collapse and Conformation of Low Molecular Mass Polyacrylic Acid an...
There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at... -
Novel protophane and cyclophane surfactants
Novel Gemini surfactants (protophanes and cyclophanes) have been synthesised as model biological anion receptors, and their critical micelle concentrations determined by surface... -
Self-assembly of GFP-HMPA protein polymer conjugates: Effect of polymer hydro...
Conjugation of therapeutic proteins to polymers is well established but most methods result in multi-site and multiple conjugation, crosslinking resulting in lack of orientation... -
Surfactant Adsorption in Multi Metal Deposition Fingerprint Enhancement
Multi metal deposition (MMD) is a new latent fingerprint enhancement technique that is extremely effective on plastics, including drug wraps and explosives wrapping; it is also... -
Rapid microfluidic phase mapping of SDS:water:butanol
Sodium dodecyl sulfate (SDS) is an anionic surfactant, extensively employed in cosmetics and personal care, as well as in pharmaceuticals and food products. Surfactants are... -
Biological membrane mimics made of deuterated lipids extracted from E. coli
Biological membrane mimics are a bottle neck in biophysical studies today. The need to develop advanced models that actually represent the properties of specific cellular... -
Mixed micelles with "green" surfactants
This proposal aims to explore aqueous phase structures and compositions of a series of mixed surfactants. Although standard surfactant mixtures have been extensively studied... -
Co-adsorption of eggshell membrane polypeptide-surfactant mixtures at oil-in-...
An eggshell membrane polypeptide is highly surface active and effective at emulsion stabilization. We explore how to use SANS to study the interfacial layers surrounding the... -
Competition at the nanoparticle surface: one polymer, two surfactants, many p...
Polymers and surfactants are key components in detergency. Understanding their interactions is essential to formulate smartly. Detergent formulations usually contain a mixture... -
SANS study of the interaction of model plant leaf waxes with non-ionic surfac...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Concentrated emulsions as proxy CO2 thickeners
The proposal aims to explore the oil-in-water (brine) high internal phase emulsion systems (HIPEs) formed by nonylphenol ethoxylate surfactants using contrast variation SANS... -
Polymer-Lipid Nanodisc Self-assembly Processes Using Stop Flow
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Polymer stabilized lipid bilayer discs... -
SANS Study of pH-Triggered Behaviour in Pluronic-Flurbiprofen Solutions: In v...
Hydrophobic drug encapsulation is one of the widely used strategies to overcome the poor adsorption and bioavailability of these drugs in vivo. Water-soluble amphiphilic... -
Bulk interactions of surfactant molecules in aqueous particle suspensions
Surfactants represent an important class of compounds owing to their ability to readily locate at interfaces, be it airliquid, liquidliquid or solidliquid. As such,... -
Structural development of magnetite chains
One dimensional (1D) magnetic nanostructures exhibit anisotropic magnetic properties and thereby differ from unstructured materials. However, magnetic chains are energetically...