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Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Inter...
In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on... -
Investigation of the surface structure of anionic surfactants induced by the ...
This proposal is part of a major EPSRC (EP/GR065705) / Unilever funded programme to develop and control the spontaneous formation of surfactant multilayer structures at... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Spray-coating plastic solar cells: New materials & innovative processes for O...
We propose to study a range of new selenium containing lower energy gap organic photovoltaic materials deposited by spray coating using neutron reflectivity. The new materials... -
SPRINTER commissioning
This dataset has no description
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Neutron reflectivity studies of the interaction of amphotericin with model ce...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin (AmB) has created a demand for novel anti-fungal agents that can circumvent the pathogens¿... -
Magnetic study of the new skyrmion-carrying material CoZnMn
Nanoscale magnetic skyrmions are swirl-like magnetisation entities that satisfy topological quantisation conditions. They can therefore not be easily unwound into another... -
Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Smectic Wetting at Nematic Surfaces
We have been studying the interaction between nematic liquid crystals and interfaces. It has been found that a surface that anchors the director in a perpendicular orientation... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Tuning the Magnetic Properties of γ-Fe2O3 Fe3O4 Thin Films for Atom Tr...
In this work we will investigate how the magnetic properties of nanometer thick iron-oxide films can be manipulated by heating them in air. Our preliminary results indicate that... -
Magnetic interactions in ferromagnetic topological insulator multilayer struc...
Topological insulators are one of the most important recent discoveries in condensed matter physics. The topological surface state can become gapped when ferromagnetic order is... -
Membrane perturbation and permeabilization by the lysosomotropic detergent MSDH
Lysosomes are subcellular organelles with acidic interiors (pH 3.5-5), containing enzymes that break down macromolecules and intracellular waste. Controlled release of lysosomal... -
Correlation between local dynamics and shape of SDS micelles:QENS study
Fast segmental dynamics of surfactants in rod-like assemblies and their correlation with microstructure is not very well understood although the structure and macroscopic... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation.... -
Mesophase transition induced by nanoparticles
In a previous SAXS experiment at Max-Lab (Sweden) we observed that the thermotropic mesophase transitional behaviour of the monoolein(MO):cholesterol:water system was... -
Vibrational Densities of States from Amorphous Nanocomposites for Novel Drug ...
In the current proposal, we require TOSCA to investigate by vibrational spectroscopy the apparent amorphous nature of the prototype drug molecule ibuprofen confined by... -
Co-surfactancy of oil-soluble and water-soluble surfactants in emulsion stabi...
The structures of emulsions formed from mixed oil-soluble and water-soluble amphiphiles (respectively derivatives of polyisobutylene, PIBSA, and polyacrylamide, PAM) will be... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also...
