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Application of direct inversion to magnetic contrast datasets.
We have developed an experimental approach using a buried magnetic layer to provide contrast in systems consisting of complex biomolecular layers tethered to gold surfaces. This... -
Antibiotic paths through the bacterial outer membrane: The strange case of va...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Antibody-polysorbate surface interactions
Of concern to the bioprocessing industry is the manner in which polysorbates included in solution formulations of antibodies affect the kinetics and equilibrium state of... -
Competitive and cooperative adsorption of lysozyme and human serum albumin
All solid surfaces in contact with biological systems form a protein corona and the nature of this corona determines the further response of the biosystem to that solid surface... -
The Effect of Core Oligosaccharide Size on the Binding of Antimicrobial Prote...
This dataset has no description
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Surface Layer Structures of Short Peptide Amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly, leading to interfacial adsorption and solution nano-aggregation.... -
Neutron reflectivity for lithium battery SEI formation
We will use neutron reflectivity to probe the formation of the passivating layer which forms on lithium battery electrodes, which ultimately governs their long term performance.... -
Assembling floating, very sparsely tethered, bilayers.
The cell membrane is a very important structure in biology and many laboratory based model systems have been developed to study it using biophysical techniques. Our particular... -
Structural investigation of nano sized CeO2 and ZnO systems
We will investigate bulk and nano size ceria and zinc oxide prepared by solvothermal methods to determine the defect chemistry associated with these solids. We will use neutron... -
The effect of fatty acids on the adsorption of HSA at the silica water interface
The primary biological function of albumins is to be fatty acid carriers. The complexation of fatty acids to the albumin is expected to have a strong effect on its adsorption... -
Characterisation of bioadhesive protein-PEG conjugates grafted to titanium su...
Summary: Titanium implants are surgically important and require a hydrophilic polymer coating to prevent biofouling in situ. Bioadhesive proteins can be covalently tethered to... -
Ion mediated surfactant adsorption on cellulose films
In recent work with Unilever we have been investigating the structure of gels formed by partially oxidised cellulose nanofibrils for use in sustainable personal care products.... -
Oriented antibody binding layers
The proposal concerns the assembly of high density antibody binding surfaces to increase the sensitivity of medical diagnostics. Previously we showed that antibody binding... -
Effect of calcium ions and ionic strength on model bilayer structure
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we... -
Nature of the protein corona on nanoparticle surfaces
When nanoparticles enter a biosytem they rapidly acquire a protein corona. The nature of the outer part of this corona will determine the response of the biosystem to the... -
Free Floating Higher Plant Membrane Mimetics
We have engaged in a long term effort to build accurate bio-mimetic systems for complex structural biology studies. Recently, we have found that thiolalkylamidealcohol... -
Protein secretion: Studying the folding and assembly of membrane proteins usi...
This dataset has no description
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Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Ca...
In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Enzyme-catalysed templating of biosilica
Summary. Silicatein in marine sponges catalyses the condensation of silica but the mechanism of layer-by-layer growth of the silica spicule is unknown since sufficient...
