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Characterising the membrane binding interaction of plant annexin Gh1
Annexins are a ubiquitous group of membrane associated proteins found in animals, plants and fungi. They are linked to wide range of functions including phospholipid... -
Adsorption of Fab and Fc from monoclonal antibody at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how different globular proteins adsorb at the oil/water interface by neutron... -
Adsorption of modified PEI / SDS mixtures at the solid-solution interface
Polymer-surfactant mixtures are extensively used in a wide range of domestic, industrial and technological applications. This proposal is part of a collaboration between Oxford... -
Neutron transmission strain tomography: a novel approach to strain mapping
Strain tomography is a novel approach to the analysis of residual strain fields that involves deconvolution of unknown distributions of residual elastic strains from redundant... -
Neutron Total Scattering of Crystalline Materials in the Gigapascal Regime
Over the past few years, extensive developments have been made in the use of neutron diffraction for structural studies of liquids and amorphous materials at high pressure.... -
Scaling Model for the adsorption of macromolecules at the oil-water interface
The aim of this proposal is the application of the scaling model for the adsorption of proteins at the oil-water interface. The adsorbed amount for a series of oils as a... -
Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Responsive polymer brushes grafted from gold nanoparticles: interaction with ...
We will use SANS to characterize dispersions of gold nanoparticles functionalized with poly(dimethyl aminoethyl methacrylate) brushes grafted from 25 nm gold nanoparticle... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Neutron reflection from 3He layer adsorbed on liquid 4He surface
More than four decades ago A. F. Andreev predicted theoretically the existence of quantum states of 3He atoms on free surface of liquid 4He . In other words, at low... -
Membrane-stacking Properties of Mutant Myelin Proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
NR study of binding of short antimicrobial alpha-helix peptides with model li...
In this work we explore how our rationally designed peptide amphiphiles bind onto lipid monolayers using neutron reflection combined with deuterium labelling to the lipids,... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
Film thickness and Ageing influences on Surfactant Distribution and Nanostruc...
Recent NR results (fig 1) have shown the ability to characterise surface segregation and nanostructuring of surfactants in PVA film. As well as the fundamental scientific... -
Self-Assembled Atmospheric Fatty Acid Aerosol Proxies: Spin-Coated Thin Film ...
We propose a simultaneous neutron reflectometry (NR)/attenuated total reflection (ATR) infra-red spectroscopy experiment on spin-coated thin films of self-assembled fatty acids... -
Structural evidence of lipopolysaccharides functioning as receptors in antimi...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Neutron reflectometry study of liquid helium surface
In our recent experiment RB1120146 we have obtained new exciting results on neutron scattering on liquid He surface. At 1.5 and 2.3K there was no difference in reflectivity... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
This dataset has no description
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Incorporating outer membrane proteins in outer membrane models
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is...
