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Free Floating Higher Plant Membrane Mimetics
We have engaged in a long term effort to build accurate bio-mimetic systems for complex structural biology studies. Recently, we have found that thiolalkylamidealcohol... -
Neutron Reflectivity Study on Multi-domain DNA Molecular Motors
DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation.... -
Adsorption of an Anionic Surfactant on Anionic Surfaces in the Presence of Ca...
In this proposal we request beamtime on the Inter reflectometer to study the unexpected adsorption behaviour of the surfactant bis(2-ethylhexyl) sulfosuccinate caesium salt... -
Understanding Surfactant-Semiconducting Polymer Interactions for Optimisation...
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Characterisation of newly ordered sapphire blocks
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Effect of saponin-rich plant extracts on skin-mimicking model lipid bilayers
Plant-derived biosurfactants of the group of saponins offer an attractive alternative to synthetic surfactants because of their unique foaming and emulsifying properties... -
Satisfying the need for contrast in antimicrobial research
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Solid-supported lipid bilayers for studying mechanosensitive ion channels: to...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,... -
The effect of dendrimer surface functionalization on the interaction with mod...
Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across... -
Aggregation phenomena inside polymer brushes: lateral structure
We will use off-specular reflectivity to probe the characteristic lateral length-scales in responsive polyelectrolyte brushes grown by surface-initiated ATRP from solid-liquid... -
Interaction of an antimicrobial peptide from Lactobacillus gasseri supernatan...
A short peptide, composed of 12 amino acids (EFVFVAHAVPVM), presenting a strongly hydrophobic character, was recently isolated from Lactobacillus gasseri supernatant (AMP12)....
