-
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
-
Benchmarking improvements in experimental design in neutron reflectometry
This dataset has no description
-
The mechanism of lipid transport in Gram-negative bacteria
The bacterial cell envelope is one of the best targets in antimicrobial development. This proposal focuses on understanding how lipids move between the membranes of the... -
Dynamics of yeast lipid membranes
A cell membrane can contain hundreds of different lipid molecules, but our understanding of the dynamics of cell membranes is very limited. As a result of a collaboration... -
Direct Observation of Gram Negative Bacterial Membrane Disruption by Supramol...
Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the... -
Kinetics of amphotericin B interaction with model human and fungal cell membr...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents. The successful development of... -
Mimicking Pathogens : Floating Gram Negative Bacterial Membranes Containing t...
Recently we have been able to show two advances in the creation of realistic models of the Gram negative bacterial outer surface for use in biophysical and structural studies.... -
Chloride Intracellular Channel insertion into Tethered Bilayer Membranes
Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer... -
Structural characterisation of vaccine-adjuvant interactions using neutron re...
This dataset has no description
-
Exploring the interactions between vesicles/viruses and supported lipid bilay...
Many biological processes occur at the interface of cells, at the so called cell membrane, such as internalization of biological nanoparticles, including virions, exosomes and... -
Effect of membrane fluidity for novel dendrimer drug interaction and uptake m...
Bacteria growing resistant to common antibiotics is a growing problem and research in new types of medicines which do not induce resistance is therefore very important. Novel... -
The Interaction of Grp1 with Membranes Containing Signalling Phospholipids
This dataset has no description
-
Conformation of lipid, DSPC and cholesterol mixture
In this proposal we intend to investigate the intermolecular interactions in a mixed phospholipid/cholesterol monolayer at the oil-water interface using neutron reflectometry.... -
Does ozone initiate damage to the main pulmonary surfactant lipid, DPPC, or c...
Exposure to ozone gas can cause inflammation of the airways and breathing difficulties. The initial reaction of ozone is thought to be predominantly with lipids present in the... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Interactions of Cationic Surfactants with Phospholipid Vesicles: Influence of...
Surfactants are frequently used in personal care products to improve the wetting and oil solubilizing qualities of the products, which also leads to the skin irritation by... -
Oxidation of a bilayer of DOPC by aqueous ozone - a chemical, kinetic and mec...
Mineral aerosol in the atmosphere is a major part of the Earths aerosol budget. Organic films on these aerosols affect the aerosols ability to promote cloud formation and... -
The influence of transmembrane potential on the orientation of antimicrobial ...
Natural antimicrobials are of great interest, since they are antibiotics that act on the biological membrane, and it is believed that this makes it far more difficult for... -
Changes of phospholipid aggregate morphology induced by phospholipase hydrolysis
We propose to look at the interaction of the aggregates two phospholipids form with two phospholipase (PL) enzymes, PLA2 and PLC, which hydrolyse different ester groups in the...
