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Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Magnetic Ground State of a New Honeycomb Iridate
A new layered iridate material, Cu2IrO3, has been fabricated. This material is isostructural with the much-studied Na2IrO3 and has a nearly ideal honeycomb structure that should... -
Investigation of phase diagrams of polysaccharides
This project concerns fundamental and strategically important research underlying the development of new drug delivery vehicles. We propose to sample phase diagram of... -
In-situ under electric field neutron diffraction at variable (low) temperatur...
Neutron diffraction experiments will be carried out on multiferroic ceramics. What is special about the measurements, is that they will be carried out under an applied electric... -
Metallomicroemulsions - a new class of supramolecularly organised metal ions
Incorporation of d- or f-block metals into ligand systems that renders a metal complex surface active or drives its partitioning into surfactant phases enables the localisation... -
A - Au/THPC/NaOH/_SANS
This dataset has no description
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Using SANS to understand the structure and behaviour of surfactants in chocolate
Molten chocolate is a semi-solid suspension of (mostly) sugar, but also cocoa and milk solids in oil. In order to allow the sugar grains to flow past each other, either when the... -
Programme Access Rosseinsky
This dataset has no description
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An exploration of the vibrational properties of energetic materials using Ine...
We have initiated a new research programme that seeks to correlate features of the crystal structures of energetic materials (explosives, propellants) with their sensitivities... -
Conformational analysis of subtilin / lipid II binary antibiotic/target membr...
Antibiotic resistance is pathogenic bacteria is a major clinical problem. Resistance to all antibiotiotic classes, currentl yin clinical use, has been reported. By contrast, the... -
Cellulose-based polyelectrolytes for microencapsulation: conformational trans...
Addition of multivalent salts to water soluble polyelectrolytes, such as sodium carboxymethyl cellulose (NaCMC), induces conformational change to the polyelectrolyte structure,... -
Effect of steroid structure on solubilisation in a series of C12 surfactant m...
The current project aims to probe (at the nanometer length scale) the relationship between the structure of a surfactant molecule, the micelles it forms in solution, and the... -
Structure-function studies of Replication Protein A, a crucial player in geno...
Replication protein A (RPA), the eukaryotic ssDNA binding protein, is a heterotrimeric protein required for almost all aspects of cellular DNA metabolism. RPA binds... -
Probing the structure of antibiotic-gold nanoparticle conjugates
In a one-pot synthesis, we are able to produce spherical gold nanoparticles capped with antibiotics, without the use of other chemicals by using the antibiotic as the reducing... -
Unlocking the Lyotropic Liquid Crystal Phases of Novel Photosurfactants
Photosurfactants (PS) demonstrate the combined ability to change their shape upon irradiation with light and self-organise into polymolecular assemblies. However, the phase... -
Unlocking the Lyotropic Liquid Crystal Phases of Novel Photosurfactants
Photosurfactants (PS) demonstrate the combined ability to change their shape upon irradiation with light and self-organise into polymolecular assemblies. However, the phase... -
Average structures of new functional oxides - HPRD
The proposal addresses the average structures of new lead-free ferroelectrics, low-temperature ionic conductors and mixed conductors which are candidate solid oxide fuel cell... -
Investigation Into The Mechanism Of Protection Of Proteins During Freeze-Drying
Protection of biological molecules during freezing and lyophilisation is of commercial importance to the pharmaceutical, medical, and food industries. Sugars and surfactants... -
Solubilisation of Drug Molecules in Nonionic Surfactant Micelles: Structural ...
This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the... -
Singlet fission materials as active quantum dot ligands for photon multipliers
Our research aims to develop plastic films that change the colour of the light that passes through them, not by absorbing certain wavelengths of light, as a simple colour filter...
