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Analysis of the role of yeast Sro9p in controlling the translation of specifi...
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Sro9p is an atypical La motif containing protein (LARP). LARPs are... -
Dbf4 recruitment by forkhead transcription factors defines an upstream rate-l...
Initiation of eukaryotic chromosome replication follows a spatiotemporal program. Current model suggests that replication origins compete for a limited pool of initiation... -
Systematic evaluation of conditional gene essentiality changes across 4 yeast...
The extent by which different genetic backgrounds affect conditional gene essentiality is understudied. Here, 4 whole-genome knockout libraries were screened to systematically... -
Base editing in yeast
The NGS data was used to analyze the frequency of base editing in yeast -
RNA Tagging in yeast
RNA Tagging experiments done in yeast -
Transcription Analysis of Clustered Essential Genes
All 14 essential genes of chrIII were clustered and reordered, and transcription of the genes was tested. We designed and constructed three types of reorganized essential genes... -
RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nu...
The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA... -
Large-scale reporter assay to assess expression and coactivator specificity o...
Three general classes of yeast protein-coding genes are distinguished by their dependence on the transcription cofactors TFIID, SAGA and Mediator (MED) Tail, but little is known... -
Saccharomyces cerevisiae YB210 GLBRCY127 transcriptome - LIMS422V1T9
RNAseq profiling of engineered S. cerevisiae during conversion of cellulosic sugars into biofuels Sample from Aerobic bioreactor containing cellulosic media -
Increased recombination frequency generates a different network of known and ...
Pooled-segregant whole-genome sequence analysis allows efficient QTL mapping of complex traits. Increasing the recombination frequency by random inbreeding of first generation... -
Sequencing data of 35 Saccharomyces cerevisiae isolates associated with beer ...
We sequenced 35 Saccharomyces cerevisiae strains using long- and short-read sequencing methods to study the genomic architecture of beer brewing isolates. Long-read sequencing... -
Experimental Co-evolution of Saccharomyces cerevisiae and Lactobacillus plant...
Experimental co-evolution with Saccharomyces cerevisiae and Lactobacillus plantarum. -
DNA Methylation-Based High-Resolution Mapping of Long-Distance Chromosomal In...
Here, we present Methyltransferase Targeting-based chromosome Architecture Capture (MTAC), a method that maps the contacts between a target site (viewpoint) and the rest of the... -
Glycolytic Enzymes Bind mRNA and Coalesce in G-bodies Essential for Cell Prol...
This experiment aimed to identify the direct RNA targets of G-body components Pfk2, Eno1, and Fba1 in budding yeast. Overall design: PAR-CLIP-seq was performed on RNAs... -
Saccharomyces cerevisiae YB210 Y128 transcriptome - LIMS 758 S4 T5
RNAseq of Saccharomyces cerevisiae YB210 Y128 evolved strain to identify transcription units and quantify gene expression during the fermentation of ethanologens in... -
Uncovering novel genetic factors controlling sphingolipid-induced mitochondri...
Lipid intermediates derived from sphingolipid metabolism are crucial regulators of mitochondrial function from yeast to humans. Among these intermediates, trans-2-hexadecenal... -
Deep mutational scanning of an ancestral protein
Assayed all combinations of amino acids at four key sites at the protein:DNA interface of two ancestral steroid receptor transcription factors -
Genetic mapping for ethanol tolerance
Ethanol, produced by S. cerevisiae fermentation, is the main biofuel used worldwide. The toxicity effect of ethanol on yeast, which inhibits industrial productivity, calls for... -
Aneuploidy as a cause of epigenetic instability and cell identity disorder
Aneuploidy and epigenetic alterations have long been associated with carcinogenesis, but it was unknown whether aneuploidy could disrupt the epigenetic states required for... -
2-deoxyglucose resistance in Saccharomyces cerevisiae
Yeast and fast-growing human tumor cells share metabolic similarities in that both cells use fermentation of glucose for energy and both are highly sensitive to the glucose...