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Solution aggregation of short peptide amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
The effect of unsaturation on the shear dependence of cationic lamellar phase...
Products such as fabric and hair conditioners are commonly in the form of di-alkyl chain cationic lamellar phase dispersion. The effects of shear on such lamellar phase... -
Quantifying the adsorption of lecithin on sucrose particles to understand cho...
Small angle neutron scattering will be used to directly quantify the adsorption of lecithin at the interface between partially deuterated sucrose particles contrast-matched to a... -
Characterisation and peptide resistance capabilities of bacterial membrane mi...
Lysylphosphatidylglycerol (LPG) is a major constituent of the plasma membrane of the bacterial pathogen methicilin resistant Staphylococcus aureus (MRSA), which has been... -
Structure of Colloidal Titania Particles in Water vs Organic Solvent
Dye sensitised solar cells, based around colloids of the wide bandgap semiconductor TiO2 with bound dyes have potential to provide a cheap,sustainable source of solar energy... -
Molecular architecture of vesicles formed by novel sterol-modified phospholipids
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
Structure of Cellulose Nanofibril Gels with Alcohols
Our group has been working partially oxidized cellulose nanofibrils which form gels in aqueous formulations. Recently we have observed that these fibrils also gel when dialysed... -
Solubilisation of Drug Molecules in Nonionic Surfactant Micelles: Structural ...
This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the... -
Aggregate structures formed by lipopolysaccharide-peptide complexes in solution
Bacterial lipopolysaccharide (LPS) is a bioactive structural amphiphilic molecule which forms the outer leaflet of the outer membrane of the Gram negative cell envelope. During... -
Interactions between phenylboronic acid modified polyacrylamides and surfactants
We are currently investigating phenylboronic acid modified polyacrylamides with variable phenylboronic acid block lengths as a route to glucose sensors with controllable... -
Characterisation of self-assembly in cationic-oligoanion mixtures: from micel...
The proposal is part of an EPSRC funded programme (EP/GR065705) on surfactant multilayer structures, and involves the interaction between ionic surfactants and oligoions. It... -
Interactions between alkylmethacrylate modifed polymers and surfactant micelles
We have observed formation of polymer-surfactant films at the air interface having a range of structures, related to their solution interactions. The films form with... -
Stable block copolymer:fullerene nanocomposites for solar cells
We propose to study the thermodynamic structures and quench dynamics of a novel block copolymer:fullerene nanocomposite towards the design of optimized charge transport pathways... -
Surfactant ionic liquids as tuneable structured media
This proposal aims to explore aqueous phase structures of a new range of ionic liquid surfactants (IL-surfs). These IL-surfs have interesting potential applications as reaction... -
Structure of the interaction between complement factor H (CFH) and complement...
Complement comprises key proteins in innate immunity that forms a major defence and clearance system in blood. CFH is the major regulator of active C3b formed from C3. C3d is a... -
Effects of pH and ionic strength on stability and structure of lipid-polymer ...
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Styrene-Maleic Acid Lipid Particles have a number of attractive... -
Zwitterion doped PEDOT:PSS bulk morphology modification as a function of dopi...
We propose to use SANS to study the intra-particle information (size, shape, interactions) of pristine and zwitterion doped PEDOT:PSS in order to have a better understanding of... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS... -
Probing the structure of polymeric foams on SANS2d ?
Polyurethane foams (PUFs) are commonly prepared by mixing Pluronic type copolymers and isocyanate reactive monomers in the presence of additives e.g. catalysts, blowing agent... -
SANS Study of pH-Triggered Behaviour in Pluronic-Flurbiprofen Solutions: In v...
Hydrophobic drug encapsulation is one of the widely used strategies to overcome the poor adsorption and bioavailability of these drugs in vivo. Water-soluble amphiphilic...
