32 datasets found

The interaction of alkyl hydroxamate with iron is of interest in mineral flotation science, corrosion control and also as a model for microbial siderophore chemistry. Long chain...

This study will focus on the structural investigations of the bilayers formed on silicon substrates in which the outer leaf consists of DOPE/LPS mixtures. We aim is to achieve...

Stabilizers of colloidal particles are often complex and their function may involve several mechanisms to impart stability of a wide range of conditions. Sodium polyacrylate is...

The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial...

The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the...

Recently (RB19100102) we have discovered that floating bilayers composed of fluid phase lipids can be produced by deposited vesicles onto charge modified oligo(ethylene...

The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will...

We grafted 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer brush from the silicon wafer surface through Cu (0) mediated controlled radical polymerization (CuCRP) to mimic...

Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the...

This proposal will exploit the unique ability of neutron reflection to characterise the adsorption of a key additive on the surface of calcite from a non-aqueous solvent and the...

AOT is also known to be very sensitive to the concentration and nature of counter-ions. When adding a sufficient amount of divalent salt to an AOT solution, a very strong Bragg...

Gram negative (-ve) bacteria possess numerous defenses against antibiotics, not the least of them being the intrinsic permeability barrier afforded by their outer membrane (OM)...

Neutron reflection will be used to reveal the structural changes from different inner membrane leaflet models upon interacting with a group of antimicrobial lipopeptides with...

Part One of the proposal is concerned with the fundamental structure of the TBM and aims to determine: (i) the impact of spacer molecule length on the dimensions of the bilayer...

Perfluoroalkyl substances (PFASs) are used extensively in industrial products although have been identified as emerging pollutants accumulating in wildlife and environment....

'Floating LSupported Bilayers' (FSB's) have become the 'standard' systems used for studying membrane systems using reflectivity at ISIS and other facilities. They are reliable,...

Perfluoroalkyl substances (PFASs) are fully fluorinated, stabile, and surface-active compounds. They contain both a hydrophobic fluorinated carbon chain and an ionizable...

We propose to use NR to study the structural features of the model wheat wax films formulated from the known main components of long chain primary alcohols and an ester. By...

Membrane Proteins (MPs) consist of about 1/3 of the proteome but the structural information available is very limited compared to that for soluble proteins. Despite this at...

The outer membrane of Gram negative bacterial is an effective barrier for many harmful agents. We have been developing and testing advanced models of the Gram negative bacterial...