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Electrospun Polybutylene Succinate Coatings for Sustainable Cardboard Packagi...
Dataset associated to the article : "Electrospun Polybutylene Succinate Coatings for Sustainable Cardboard Packaging: Structure-Property Relationships". The dataset contains :... -
Self assembly of thermoresponsive gels
Thermoresponsive gels are widely used for tissue engineering and drug delivery applications. They consist of a thermoresponsive polymer that self-assembles in a 3D network when... -
How does tendency to adopt different secondary structures from antimicrobial ...
This work aims to exploit the unique capability of neutron reflection to examine how 2 antimicrobial lipopeptides that tend to adopt different secondary structures bind to model... -
Neutron Reflection Studies on Adsorption of Lauroyl-L-Carnitine (C12-L-Caniti...
Acyl L-Carnitines are a group of novel surfactants with attractive physical and biological properties associated with their head group charge features. This work proposes to use... -
Conformational Evaluation of Biodegradable Model Polymer-Drug Conjugates
Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The... -
Protein nanosheets assembled structures at the air-water interfaces for cell ...
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Interaction of Low Density Lipoproteins (LDL) with Model Mammalian Cell Membr...
Atherosclerosis and subsequent clinical complication is one of the biggest killers in the western world, with a death toll reaching 16.7 million deaths per year. Although many... -
Stabilising emulsions with protein-surfactant mixtures.
Hydrophobins, hfb2, are secreted fungal proteins, which are strongly surface active and possess powerful emulsion and foam stabilising properties. Understanding their... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Neutron Reflection at the Mica Water Interface
Mica is an exceptionally important mineral in surface science, which until now has been inaccessible by neutron reflection. Here we propose a novel attachment method unlocking... -
Aggregation behaviour of aqueous hairy rod conjugated polyelectrolyte/surfact...
Small angle neutron scattering (SANS) will be used to characterise the structures of aggregates formed between the anionic conjugated polyelectrolyte... -
How does oxidative damage change peptide membrane insertion?
The insertion of peptides and proteins into cell membranes is crucial for the functioning of cells, and also for the functioning of a variety of antibacterial reagents. Cells... -
Co-adsorption of monoclonal antibodies and non-ionic surfactants at the air/l...
Nonionic surfactants usually do not show affinity to proteins and they work via competitive surface and interfacial processes in a binary mixture with protein. However, we show... -
INTRACELLULAR WATER AS A SECONDARY DRUG TARGET IN CHEMOTHERAPY: THE IMPACT OF...
Water plays a vital role in biochemical processes in a living organism. Within a cell, intracellular water structure/dynamics are known to be changed by metabolites or extrinsic... -
SANS Study of the interaction of model wax alcohols with non-ionic surfactant...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Elucidating molecular mechanism of membrane disruption by designed α-hel...
We have previously shown that peptides such as G(IIKK)4I-NH2 (G4) can kill bacteria and inhibit cancer cell growth whilst remaining benign to mammalian host cells. We have also... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Interaction of polypeptide with surfactant on the surface of water
This proposal constitutes part of our ongoing study towards understanding the adsorption of collagen based polypeptide and its interaction with ionic surfactants at the... -
Assembly of supramolecular nanotubes into tubisome structures from self-assem...
Cyclic peptide-polymer conjugates can readily self-assembly into long nanotubes, and are being extensively studied for biomedical applications. Recently, we have conjugated a...