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Structure and Water Binding in Natural Deep Eutectic Solvents
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. However instead of being composed of a salt, the... -
Adsorption of Membrane-Protein Containing Nanodiscs at Lipid Interfaces
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Poly(Styrene-Maleic Acid) stabilized lipid nanodiscs can be... -
Biomolecular Cryoprotection in Deep Eutectic Solvents
Protecting biomolecules, such as proteins and enzymes, from the effects of cooling and freezing is important for the storage and handling of pharmaceuticals. Deep eutectic... -
Counterion binding to nonionic micelles: effect on interactions with silica
This proposal continues our research on ion binding to surfactant micelles. Our recent work demonstrates that the details of water structure around micelles are now accessible... -
Encapsulation of Hydrophobic Species in Surfactant Micelles
Our recent work demonstrates that the details of water structure around micelles are now accessible using Empirical Potential Structure Refinement methods combined with neutron... -
A study of protein adsorption via chelating lipids within a solid supported l...
The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played... -
Silica binding to nonionic micelles: effect of headgroup size
This proposal continues our research on ion binding to surfactant micelles. Our recent work demonstrates that the details of water structure around micelles are now accessible... -
Alcohols in Cationic Surfactant Micelle Solutions
This proposal continues our studies of water and small molecule binding around surfactant micelles using NIMROD, to obtain previously inaccessible details of their molecular... -
Interpreting the Effect of Small Ions on Charged Lipid Membranes
We propose a study to extend the understanding of the influence of salt on the structure of DPPG membranes floating on an al-PC bilayer. We have previously demonstrated the... -
Micelle structures in unequal mixtures of amino-acid surfactants
In a previous proposal we started to study the micellar structures formed from biodegradable surfactants synthesised using amino acids as the headgroups. The aim of this work is... -
Micelles in Deep Eutectic Solvents
Deep Eutectic Solvents (DES) are molecular mixtures similar to ionic liquids, having melting points below room temperature. However instead of being composed of a salt, the... -
Curvature effects in polyelectrolyte-surfactant solution interactions
This proposal continues our investigations into polyelectrolyte-surfactant solutions which form thin films at the air-solution interface. Our previous work has investigated the... -
Ion mediated surfactant adsorption on cellulose films
In recent work with Unilever we have been investigating the structure of gels formed by partially oxidised cellulose nanofibrils for use in sustainable personal care products.... -
Surfactant chain length effects on styrene incorporation in PEI/surfactant films
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the highly... -
Cavitation processes in gas desorption experiments.
The aim of the experiment is to improve understanding of the onset of the cavitation process in desorption, in order to, ultimately, better understand adsorbate behaviour and... -
Anion effects on self-assembly in deep eutectic solvents.
Deep Eutectic Solvents (DES) are mixtures of an organic salt with a hydrogen bond donor that form strong interactions which hinder crystallisation. DES share many features with... -
Probing binary mixtures of hard spheres
As part of a larger programme we aim to test densely-packed binary mixtures of monodisperse hard sphere powders to determine local structure, to correlate with ratio of... -
Time Resolved Studies on Inorganic Film Formation at the Air-Solution Interface
In a recent SURF experiment on the formation of silica films templated with cat-anionic/polymer complexes we found that the film growth and evolution occurs on a faster time... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
Encapsulation of Hydrophobic Species in Surfactant Micelles
Our recent work demonstrates that the details of water structure around micelles are now accessible using Empirical Potential Structure Refinement methods combined with neutron...