This research work has been carried out as a part of Ph.D thesis of Rebecca G, funded by TANII project entitled ''E-fish health surveillance and monitoring network to improve fisheries production in Tamil Nadu". Ph.D research guide and Principal investigator of the project: Dr. A. Uma Ph.D, Professor and Head, State Referral Laboratory for Aquatic Animal Health, Tamil Nadu Dr.J.Jayalalithaa Fisheries University, Madhavaram campus, Chennai - 600051.</p><p>This project contains RNA seq data of 4 samples</p><p>Liver tissue from apparently healthy Oreochromis niloticus (2 samples) - 3HC, 4HC</p><p>Liver tissue from TiLV - infected Oreochromis niloticus (2 samples) - 5IF, 7IF