Study of gelation dynamics of a temperature-responsive polymer hydrogel

DOI

Temperature-responsive polymer hydrogels are of increasing interest for biological applications such as smart drug release and DNA sequencing, however no studies on the microscopic gelation and melting dynamics are available so far. We propose therefore to investigate the dynamics of thermoreversible polysaccharide gel forming systems by using Neutron Spin Echo (NSE). In this way we will be able to investigate for the first time the temperature and aging dependence of the gelation and melting process at a very early stage. Through a combination of X-ray Photon Correlation Spectroscopy (XPCS), NSE and previously reported Dynamic Light Scattering (DLS) data [3] we expect to retrieve complementary information by exploring a wide Q-range, and to obtain for the first time a complete picture of the difference in the evolution of the system towards the two gel phases (clear and turbid gels) and their corresponding melting. This information is fundamental for a deeper understanding of the gelation and melting in thermoreversible, physical gelation processes, and is of course fundamental for any practical application.

Identifier
DOI https://doi.org/10.5291/ILL-DATA.9-11-1626
Metadata Access https://data.ill.fr/openaire/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=10.5291/ILL-DATA.9-11-1626
Provenance
Creator Ruta, Beatrice; Rinaudo, Marguerite; Czakkel, Orsolya; Nervo, Roberto; Chushkin, Yuriy
Publisher Institut Laue-Langevin
Publication Year 2014
Rights OpenAccess; info:eu-repo/semantics/openAccess
OpenAccess true
Representation
Resource Type Dataset
Size 313 MB
Version 1
Discipline Particles, Nuclei and Fields