As part of the Perma-X airborne campaign led by the Alfred Wegener Institute in 2021, we collected super-high-resolution multispectral imagery of permafrost landscapes with the Modular Aerial Camera System (MACS), developed by the German Aerospace Center. From these images, we photogrammetrically processed four-band orthophotos (blue, green, red, near-infrared) and digital surface models at a spatial resolution of 10 cm, as well as photogrammetric point clouds in RGB and NIR at 8.95 pts/m² and 3.16 pts/m², respectively. This dataset covers approximately 22.13 km² of drained thermokarst lake basins on the northern Seward Peninsula in Alaska, with all images collected on 9 July 2021. This super-high-resolution dataset provides opportunities for generating detailed training datasets of permafrost landform inventories, a baseline for change detection for thermokarst and thermo-erosion processes, and upscaling of field measurements to lower-resolution satellite observations.