We performed high-throughput sequencing on regenerating samples and compared the data with regular embryonic and postlarval development of Sycon ciliatum. Our comparative transcriptomic analysis illuminates that sponge regeneration is equally dynamic as embryogenesis. Overall design: By using height throughput sequencing to measured gene expression in regenerating samples at 7-time points spanning from 1 to 24 days including days 1, 2, 3-4, 6-8, 10-12, 16-18 (PJUV) and 21-24 (JUV)