Reflectin, so named because of its high refractive index, is a protein expressed exclusively in cephalopods and forms reflectors responsible for dynamic iridescence and structural color change. Intrinsic self-assembly, along with higher-order assembly tightly modulated by potential neurotransmitters, provide insights into the formation of multilayer reflector in iridophores, and form the basis of structural color change in cephalopods. Here we propose to study the internal dynamics of reflectin using QENS. Our results will show whether there are significant differences in the dynamics of reflectin, upon adding small molecules (such as imidazole) that will enable its self-assemly. This study will help elucidate the molecular mechanisms of reflectin-mediated dynamic structural coloration and bio-invisibility, and with a perspective for bioinspired photonic materials.