Small RNAs from the Great Pond Snail Lymnaea stagnalis: Samples from reproductive tract and (foot-) muscle

PIWI proteins and a specific class of small non-coding RNAs, termed Piwi interacting RNAs (piRNAs), suppress transposon activity in animals on the transcriptional and post-transcriptional level, thus protecting genomes from detrimental insertion mutagenesis. While in vertebrates the PIWI/piRNA system appears to be restricted to the germline, somatic expression of piRNAs directed against transposons is widespread in arthropods, likely representing the ancestral state for this phylum. Here, we show that somatic expression of PIWI genes and piRNAs directed against transposons is conserved in mollusks, suggesting that somatic PIWI/piRNA expression was already realized in an early bilaterian ancestor. We further describe lineage specific adaptations regarding transposon composition of piRNA clusters and show that different piRNA clusters are dynamically expressed during oyster development. Finally, bioinformatics analyses suggest that different populations of piRNAs participate in the ping-pong amplification loop in a tissue specific manner.

Identifier
Source https://data.blue-cloud.org/search-details?step=~0127F55D4B5A609F30B0111B04934068C0CFBF123FB
Metadata Access https://data.blue-cloud.org/api/collections/7F55D4B5A609F30B0111B04934068C0CFBF123FB
Provenance
Instrument BGISEQ-500; BGISEQ
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Point 2017-06-01T00:00:00Z