The study aimed to investigate the difference in the susceptibility of coral taxa and profiling coral-associated microbial prokaryotes and eukaryotes (microbiome). Healthy and bleached corals of four genera (Acropora sp., Platygyra sp., Pocillopora sp., and Porites sp.), seawater, and sediment samples were collected from Phuket province of Thailand during the global bleaching event (May, 2016).