This dataset is a component of the PAN-Arctic data collection of benthic BIOtas (PANABIO) and has been collated during the Census of Marine Life project Arctic Ocean Diversity (ArcOD; http://www.arcodiv.org/). It contains a total of 1,442 abundance and wet biomass records of 319 macro- and megabenthic taxa (species to family level) identified in 13 Agassiz trawl catches and 15 giant box corer samples taken at 28 stations located in the Beaufort Sea at water depths of 28–74 m during one cruise in 2011. The dataset is also available in a PostgreSQL-based data warehouse that can be accessed and queried through an open-access frontend web service at https://critterbase.awi.de/panabio.