Radiotherapy and androgen deprivation in combination after local surgery (RADICALS) trial was made up of several overlapping comparison studies on men who had prostate cancer and surgery to remove their prostate. The trial aimed at looking at whether having radiotherapy should also go along with hormone therapy and for how long. This is a data pack containing the protocol, statistical analysis plan (SAP), data dictionary and annotated CRFs. This is provided to allow researchers to consider this trial and to find enough information to know if they wish to apply to for a copy of the pseudonymised dataset. Access to the data can be requested here: https://www.mrcctu.ucl.ac.uk/our-research/other-research-policy/data-sharing/.