Production mechanism of polymersomes

DOI

In the field of cancer research, radionuclide therapy is proven to be one of the only viable alternatives to chemotherapy in the case of metastasized cancer. In this context, polymersomes are attracting increasing interest as a an alternative to liposomes due to their ability to encapsulate a broad range of drugs, biomolecules and radionuclides. Because of the good synthetic control in the polymer industry, polymersomes, compared to liposomes, have a higher variability as well as an enhanced physical and chemical stability. The main challenge in the production of polymersomes is up scaling the formation process which required understanding of the formation mechanism. We propose to investigate the important steps in the formation mechanism using neutron scattering techniques.

Identifier
DOI https://doi.org/10.5286/ISIS.E.98001085
Metadata Access https://icatisis.esc.rl.ac.uk/oaipmh/request?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:icatisis.esc.rl.ac.uk:inv/98001085
Provenance
Creator Dr Jeroen Plomp; Ms Emily Remmelts; Dr Adam Washington; Dr Antonia Denkova
Publisher ISIS Neutron and Muon Source
Publication Year 2021
Rights CC-BY Attribution 4.0 International; https://creativecommons.org/licenses/by/4.0/
OpenAccess true
Contact isisdata(at)stfc.ac.uk
Representation
Resource Type Dataset
Discipline Chemistry; Natural Sciences
Temporal Coverage Begin 2018-09-17T23:00:00Z
Temporal Coverage End 2018-09-21T07:48:58Z