Replication data for: The spatial landscape of Cancer Hallmarks reveals patterns of tumor ecology and drug sensitivity

DOI

No description.This dataset contains spatial transcriptomics data used to analyze the spatial distribution of biological processes associated with cancer hallmarks in human tumor samples. The data come from untreated primary tumors from multiple cancer types and allow the study of gene expression activity across different regions of the tumor and its surrounding microenvironment.

The dataset includes gene expression matrices, spatial coordinates associated with each measurement point, and sample metadata. These data enable the identification of spatial patterns of molecular activity, comparison of functional organization across tumors, and exploration of the relationship between tumor heterogeneity and characteristics of the tumor microenvironment.

The dataset may be useful for researchers in bioinformatics, cancer biology, and spatial transcriptomics who aim to study the molecular organization of tumors, develop spatial analysis methods, or investigate relationships between tumor biological processes and treatment response.

Identifier
DOI https://doi.org/10.34810/data3067
Related Identifier Cites https://doi.org/10.1016/j.celrep.2024.115229
Metadata Access https://dataverse.csuc.cat/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34810/data3067
Provenance
Creator Porta-Pardo, Eduard ORCID logo; Esteller, Manel ORCID logo; Grases Mendoza, Daniela ORCID logo; Musulen, Eva ORCID logo; Sibai, Mustafa ORCID logo
Publisher CORA.Repositori de Dades de Recerca
Contributor Porta-Pardo, Eduard
Publication Year 2026
Funding Reference https://ror.org/01bg62x04 2021 SGR 01494 ; https://ror.org/003x0zc53 MCIN/AEI/10.13039/501100011033 ; https://ror.org/00k4n6c32 ERDF through PID2021-125282OB-I00
Rights CC BY 4.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/licenses/by/4.0
OpenAccess true
Contact Porta-Pardo, Eduard (Institut de Recerca contra la Leucèmia Josep Carreras)
Representation
Resource Type Experimental data; Dataset
Format image/jpeg; application/x-hdf5; text/plain; application/json; image/png; text/csv
Size 2038678; 2203772; 2319116; 2124408; 1619380; 2034306; 2048782; 2491640; 1975339; 1957538; 2237904; 2129407; 2109104; 2308822; 2012994; 2113193; 1703227; 1833273; 2031492; 1701284; 2037008; 1824627; 2078707; 1576695; 1883809; 1845520; 2436843; 2481758; 2531119; 2068000; 2821517; 2664894; 2232151; 2723637; 2214588; 2808008; 2775413; 2756217; 2357440; 2842221; 2345367; 2602528; 2805851; 2721062; 2345350; 2261173; 2598918; 2294982; 2651695; 2720006; 2739791; 2733347; 21128188; 19915965; 37859856; 38533020; 24341954; 16353516; 34793122; 10499111; 26843489; 11935241; 24169716; 23563513; 32256369; 31143718; 16063243; 7651448; 24311067; 21654216; 11155869; 31438413; 15072321; 20449253; 29726408; 25367536; 30782329; 33445586; 2108; 145; 156; 155; 164; 165; 154; 146; 163; 5188121; 5801885; 6416860; 4600182; 5628951; 5825854; 5888998; 5983612; 5644791; 6709205; 5868452; 6638608; 5449826; 5968728; 4640660; 5680369; 4532928; 7385367; 4979537; 4962554; 6098967; 5731872; 6829133; 5982231; 6150400; 5884123; 527611; 459900; 523053; 476248; 485978; 505310; 497227; 530103; 542771; 491776; 500059; 526900; 439952; 527220; 428596; 470642; 525698; 595608; 533447; 591184; 565796; 547906; 561358; 577530; 603578; 674924; 184343; 184310; 184330; 184368; 184186; 184154; 184241; 184477; 184376; 184307; 184240; 184287; 184283; 184471; 184271; 184222; 184591; 180058; 184395; 184356; 184284; 184371; 184262; 184339; 184385; 184341
Version 1.0
Discipline Life Sciences; Medicine