The controlled folding of individual polymer chains into single-chain polymeric nanoparticles(SCPNs) has received considerable attention over the last couple of years. By combining the fields of small molecule self-assembly and polymer chemistry, unique macromolecular architectures are obtained. Not only are such systems interesting from a fundamental point of view, because of their resemblance to protein, their unique ability to create nanoparticles with well-organized structured domains makes it a modular platform for applications like catalysis, sensing and drug delivery. Since structure and function are closely related, we aim to acquire more in-depth insight in the folding behavior, structure and the dynamics of such polymeric systems. Hereto, we study water-soluble polymers grafted with structuring supramolecular motives, as well as aliphatic units using scattering techniques.