Single-tooth loss is often treated with implant-retained crowns. Conventional screw implants require invasive surgery, whereas root-analogue implants can be placed directly into extraction sockets. Yet, past attempts failed due to lacking a periodontal ligament (PDL) analogue, vital for physiological attachment. Our project (BMBF: BioPIZ) addresses this by creating a bionic replica of the tooth root surface via additive manufacturing and post-processing, enhanced with a 3D-bioprinted extracellular matrix layer to support periodontium regeneration. The proposed synchrotron nanoCT experiment will generate sub-micrometer 3D data of native cementum, providing the digital blueprint for a biomimetic implant surface. This approach aims to ensure physiological integration of BioPIZ implants and prevent complications such as peri-implantitis, bone resorption and mucositis, advancing dental implantology toward truly biomimetic, root-analogue solutions.