Replication Data for: Long-term dietary intervention with low Phe and/or a specific nutrient combination improve certain aspects of brain functioning in Phenylketonuria (PKU)

DOI

48 Homozygous wild-types (WT, +/+) and 96 PKU BTBRPah2 (-/-) male and female mice started dietary treatment on postnatal day 31 up to 10 months of age in the following six groups: WT control diet (WT C-HP), WT normal diet plus specific nutrient combination (WT SNC-HP), PKU normal diet (PKU C-HP), PKU normal diet plus specific nutrient combination (PKU SNC-HP), PKU low-Phe diet (PKU C-LP), and PKU low-Phe diet plus specific nutrient combination (PKU SNC-LP). Mice were tested three times (4,7, and 10 months) after treatment initiation during four behavioural tasks: open field (OF), novel object recognition task (NOR), spatial object recognition task (SOR), and balance beam task (BB). The results are stored in three zipped folders:

Measurements.zip: Excel files with the results of the various behavioral tasks at 4, 7 and 10 months of age StatisticalAnalyses.zip: SPSS files (.sav) of the various behavioral tasks Neurotransmitters: Results and statistical analysis of the various neurotransmitter levels per mouse

Identifier
DOI https://doi.org/10.34894/KN3EZU
Metadata Access https://dataverse.nl/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34894/KN3EZU
Provenance
Creator Bruinenberg, Vibeke M.; van Vliet, Danique; van der Goot, Els; de Vries, Minke L.; Counotte, Danielle S.; Kuhn, Mirjam; van Spronsen, Francjan J.; van der Zee, Eddy A.
Publisher DataverseNL
Contributor van der Zee, Eddy A.
Publication Year 2019
Rights CC0 Waiver; info:eu-repo/semantics/openAccess; https://creativecommons.org/publicdomain/zero/1.0/
OpenAccess true
Contact van der Zee, Eddy A. (Groningen Institute of Evolutionary Life Sciences)
Representation
Resource Type Dataset
Format application/zip
Size 686148; 16311; 120043
Version 1.0
Discipline Life Sciences; Medicine