The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7 day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, as well as a number of biochemical markers. Purpose: To study the pathogenesis of atherosclerosis and its related diseases 1016 individuals all aged 70 (50%) were investigated 2001-2003. Reinvestigations were performed at age 75 and 80.

PIVUS-studien startade 2001 med ett slumpmässigt urval av 1000 individer i åldern 70 år, boende i Uppsala. Det primära syftet var att undersöka den prediktiva kraften i olika mätningar av endotelfunktion och arteriell efterlevnad. Syfte: Att studera uppkomsten av atheroscleros och dess följdsjukdomar. Vid baslinjemätningen, 2001-2003, deltog 1016 70-åringar. Dessa följdes upp vid 75- och 85-års ålder.

Probability: Simple random

Sannolikhetsurval: obundet slumpmässigt urval

Probability

Sannolikhetsurval

Self-administered writings and/or diaries: paper

Självadministrerad text och/eller dagböcker: papper

Laboratory experiment

Laboratorieexperiment

Physical measurements and tests

Fysiska mätningar och tester

Self-administered questionnaire: paper

Självadministrerat frågeformulär: papper

Participant laboratory observation

Deltagande laboratorieobservation