Replication data for the article "Dynamic light scattering unveils stochastic degradation in large-pore mesoporous silica nanoparticles" The article studies the mechanism of hydrolysis of large-pores mesoporous silica nanoparticles. These nanoparticles can be very useful for the encapsulation and the release of biomolecules. Understanding their dissolution is therefore important. DLS techniques, in millimetric and micrometric volumes, are used in this study as a new tool to monitor the diameter and concentration of nanoparticles in the colloids. Unexpectedly, we found out that the diameter of the nanoparticles remained constant throughout the study, whereas the concentration decreased following a mono-exponential decay law. These observation led us to conclude that the nanoparticles stochastically fragilize and completely vanish, whereas intact nanoparticles can be found until the end of the process.

TriStar II Plus, 3.04

Origin, 8.1

Nanokin, 2.0