This dataset provides a consistent and comprehensive outlook of global wastewater production, collection, treatment and re-use at both the country-level and 5 arc-min resolution (gridded) for the year 2015. Country-level estimates of wastewater reported from various sources are used as basis, supplemented with predictions based on multiple linear regression using social, economic, hydrological and geographical predictor variables. Country-level wastewater data are provided in both volume flow rate (million m3 yr-1) and percentage terms. Wastewater data is downscaled to gridded (5 arc-min; m3 yr-1) estimates based on simulations of domestic and industrial return flows from the Water Futures and Solutions (WFaS; Wada et al., 2016) using the approach developed for PCRaster GlOBal Water Balance model (PCR-GLOBWB2; Sutanudjaja et al (2018)). Estimates of downscaled wastewater treatment and re-use are validated based on wastewater treatment plant capacities reported in various databases.