The spatial variation of the persistence length along Widom-601 DNA

DOI

The stiffness of DNA, quantified by the persistence length, is a property that dictates much of the conformational forms and behavior of the molecule. At the moment it is not clear how the persistence length changes along the molecule due to base pair sequence or external effects like temperature. We aim to shed some light in the matter by recording SANS curves of a couple of known short chain sequences during the melting transition or thermal denaturation of DNA. From the SANS curves we expect to infer the radius of gyration of the molecules and then relate it to the persistence length through theory models. Comparing these results for both sequences and the different temperatures one could imply what are the effects of base pair sequence and temperature in this important parameter of the DNA.

Identifier
DOI https://doi.org/10.5291/ILL-DATA.9-13-665
Metadata Access https://data.ill.fr/openaire/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=10.5291/ILL-DATA.9-13-665
Provenance
Creator Rodriguez, Adrian Gonzalez; Wildes, Andrew; Porcar, Lionel; Roda, Marta Marty; Peyrard, Michel; Theodorakopoulos, Nikos; Lopez, Santiago Cuesta
Publisher Institut Laue-Langevin
Publication Year 2017
Rights OpenAccess; info:eu-repo/semantics/openAccess
OpenAccess true
Representation
Resource Type Dataset
Size 1 GB
Version 1
Discipline Particles, Nuclei and Fields