Structural Biology Core Facility (SBCF) was established in 2018 at the Malopolska Centre of Biotechnology, Jagiellonian University to support both crystallographers and non-expert researchers in studying basic biological questions with the use of macromolecular crystallography and cryoEM. Researchers in SBCF support several research groups from Krakow in all stages of structure determination starting from planning, through crystallization and optimization, crystal fishing, data collection and phasing, and model building. Depending on the need we measure approximately 1500 crystals per year using various European light sources but primarily BESSY II and ESRF.