Nanodiscs are self-assembled structures that consist of a bilayer of phospholipids controlled in diameter by a polymer or protein belt. We have already shown that such discs stabilised by the negatively charged poly (styrene-alt-maleic acid) (PSMA) will adsorb at the silicon-water interface when a lipid monolayer is present, but not on the bare silicon surface. Here we propose to repeat these measurements using a new polymer to stabilise the discs. This polymer, poly (styrene-co-maleimide) (PSMI) which is positively charged also forms discs, but in a different pH range to PSMA. This change is expected to modify the behaviour of adsorption, particularly on the bare silicon substrate and also allows the potential to remove the polymer after disc adsorption by simply modifying the pH and so destabilising the discs. This may offer a new method of making floating bilayers.