Cholesteryl Ester Transfer Protein (CETP) as a Drug Target for Cardiovascular Disease


Contains data and computer scripts to generate the figures underlying the manuscript: Cholesteryl Ester Transfer Protein (CETP) as a Drug Target for Cardiovascular Disease.The Scripts and deposited data This directory contains R and python scripts along with the data necessary to generate the results described in the manuscript: 'cholesteryl ester transferprotein (CETP) as a drug target for cardiovascular disease'. ## Directory content .├──├── scripts├── figures├── MR_data├── TRIAL_data└── PICKLED_dataThe scripts directory contains the computer codes necessary to generate the figures which get saved to the figures directory.The scripts source data from the MR_data and TRIAL_data directories. The PICKLED_data directory contains the python pickled files from which we extracted the .csv files in MR_data -- these files can be ignored. ## Computer scriptsThe directory root contains various R (.R) and python (.py) scripts that will process the data files. It also contains a cetp_conda_env.yml file to conda install the necessary R and python modules:cd scriptsconda env create -f cetp_conda_env.ymlThis creates the cetp conda environment. To generate the figures, please run the following bash script:# run from the scripts directory./ Input and output scripts/ Takes the MR_data .tsv files and returns Figures 2 and 5. scripts/MR_metabolites.R: Takes the MR_data .tsv/csv files and returns Figure 4. scripts/MR_forestplots.R: Takes the MR_data .tsv files and returns Figure 3. scripts/RCT_forestplots.R: Takes the TRIAL_data .xlsx files and returns Figure 1.## ContactPlease contact Floriaan Schmidt for any queries: .

Related Identifier
Metadata Access
Creator Schmidt, Floriaan ORCID logo
Publisher University College London UCL
Contributor Figshare
Publication Year 2021
OpenAccess true
Contact researchdatarepository(at)
Language English
Resource Type Dataset
Discipline Life Sciences; Medicine