Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice

Microbiota disorder plays a role in the pathogenesis of several disorders associated with intestinal damage caused by antibiotics. Tributyrin , as a precursor of butyric acid, has a key role in anti-inflammatory and intestinal barrier repair effects through slowly releasing butyric acid. However, its roles in gut microbiota disorder caused by antibiotics remain unclear. In this study, we established an intestinal microbiota disorder model by ceftriaxone sodium was used in gavage to investigate the effects of different doses of tributyrin for restoring gut microbiota and intestinal injury.

Identifier
Source https://data.blue-cloud.org/search-details?step=~012BC63BD3201195AEAD9304B0BCF013C1E00605E68
Metadata Access https://data.blue-cloud.org/api/collections/BC63BD3201195AEAD9304B0BCF013C1E00605E68
Provenance
Instrument Illumina NovaSeq 6000; ILLUMINA
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Temporal Point 2022-01-01T00:00:00Z