Loading self-assembled fluorinatedphases with hydrophobic drugs

DOI

The overall aim of this body of work is to design self-assembled soft matter phases for the administration of pharmaceuticals, with the current focus on understanding phases as they are loaded with drug molecules. This initial work will provide proof-of-principle with simple, model compounds. We have already selected promising phases that exhibit the desired structural, rheological and diffusion characteristics. However, we need to understand how the phase characteristics (internal structure such as lamellar spacings, microstructural phase separations) change when the phases are loaded with active molecules. These experiments will highlight structural and mechanistic features crucial to developing these materials further.

Identifier
DOI https://doi.org/10.5291/ILL-DATA.9-10-1309
Metadata Access https://data.ill.fr/openaire/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=10.5291/ILL-DATA.9-10-1309
Provenance
Creator Garvey, Christopher; Grillo, Isabelle; Mutch, Kevin; Dagastine, Raymond; Tabor, Richard
Publisher Institut Laue-Langevin
Publication Year 2014
Rights OpenAccess; info:eu-repo/semantics/openAccess
OpenAccess true
Representation
Resource Type Dataset
Size 211 MB
Version 1
Discipline Particles, Nuclei and Fields